Basic information Safety Supplier Related

KB 3022

Basic information Safety Supplier Related

KB 3022 Basic information

Product Name:
KB 3022
Synonyms:
  • KB 3022
  • 2-[4,5-Bis(4-methoxyphenyl)thiazol-2-yl]-1H-pyrrole-1-acetic acid ethyl ester
  • KBT-3022
  • ethyl 2-(2-(4,5-bis(4-methoxyphenyl)thiazol-2-yl)-1H-pyrrol-1-yl)acetate
  • ethyl 2-[4,5-bis(4-methoxyphenyl)thiazol-2-yl]-pyrrole-1-acetate
  • KB3022 (KBT3022
  • 1H-Pyrrole-1-acetic acid, 2-[4,5-bis(4-methoxyphenyl)-2-thiazolyl]-, ethyl ester
  • Cyclooxygenase,KBT-3022,Pamicogrel,Inhibitor,inhibit,KBT 3022,COX
CAS:
101001-34-7
MF:
C25H24N2O4S
MW:
448.53
Mol File:
101001-34-7.mol
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KB 3022 Chemical Properties

Melting point:
132.5-135.5°
Boiling point:
600.3±65.0 °C(Predicted)
Density 
1.22±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMF:10.0(Max Conc. mg/mL);22.0(Max Conc. mM)
DMF:PBS (pH 7.2) (1:1):0.5(Max Conc. mg/mL);1.1(Max Conc. mM)
DMSO:5.0(Max Conc. mg/mL);11.0(Max Conc. mM)
form 
A crystalline solid
pka
2.68±0.10(Predicted)
color 
Off-white to pink
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Safety Information

Toxicity
LD50 orally in male mice: >3000 mg/kg (Yoshino)
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KB 3022 Usage And Synthesis

Biological Activity

Pamicogrel (KBT3022) is an inhibitor of cyclooxygenase (COX) with platelet anti-aggregation properties.

in vitro

KB 3022 is a cyclooxygenase inhibitor with platelet anti-aggregatory properties which is under development by Kanebo for chronic arterial occlusion. It also has potential in both prophylaxis and treatment of ischemic brain injury.

target

KB 3022Supplier

MedChemexpress LLC
Tel
021-58955995
Email
sales@medchemexpress.cn
Shanghai Worldyang Chemical Co.,Ltd.
Tel
021-021-56795766
Email
sales@worldyachem.com
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696,15000506266 15000506266
Shanghai Chaolan Chemical Technology Center
Tel
021-QQ:65489617 15618227136
Email
Sales@ATKchemical.com
MQ (shanghai) Pharmaceuticals Co., Ltd.
Tel
13761635123
Email
1014988033@qq.com
TargetValue
COX
()