10-formyldihydrofolate Chemical Properties

Density 

1.67±0.1 g/cm3(Predicted)

solubility 

Aqueous Acid (Slightly), Aqueous Base (Slightly)

pka

3.38±0.10(Predicted)

form 

Solid

color 

Orange to Very Dark Brown

Stability:

Hygroscopic, Temperature Sensitive

10-formyldihydrofolate Usage And Synthesis

Uses

10-Formyl-7,8-dihydrofolic acid is a novel folate found in methotrexate-treated cells. 10-Formyldihydrofolate (H2folate) has not been found as a component of intracellular folates in normal tissues but has been identified in the cytosol of methotrexate (MTX)-treated MCF-7 breast cancer cells and normal human myeloid precursor cells.

Definition

ChEBI: 10-formyldihydrofolic acid is the 10-formyl derivative of dihydrofolic acid. It is a conjugate acid of a 10-formyldihydrofolate(2-).

10-formyldihydrofolate(28459-40-7)Related Product Information

• 5,10-DiforMyl-5,6,7,8-tetrahydro Folic Acid
• 5,10-Methylene-THF
• (2S)-2-[[4-[[(6S)-2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6- yl]methylamino]benzoyl]amino]pentanedioic acid
• 10-Formylfolic Acid
• Calcium Levofolinate EP Impurity E
• Calcium levofolinate
• Folinic Acid IMpurity H
• Folinic Acid IMpurity E
• Calcium folinate
• Folinic Acid IMpurity G
• Folinic Acid IMpurity B
• IMp. D (EP): 4-[[(2-AMino-4-oxo-1,4-dihydropteridin-6-yl)Methyl]aMino]benzoic Acid (Pteroic Acid) O
• Folinic Acid IMpurity C
• Folic Acid Related Compound A/Calcium Formyltetrahydrofolate