Basic information Safety Supplier Related

RHEIN-8-GLUCOSIDE

Basic information Safety Supplier Related

RHEIN-8-GLUCOSIDE Basic information

Product Name:
RHEIN-8-GLUCOSIDE
Synonyms:
  • calcium,3-carboxy-9,10-dioxo-5-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]anthracene-1,8-diolate
  • Rhein-8-glucoside calcium salt
  • Rhein-8-O-β-D-glucopyranoside
  • Rhein-8-O-beta-D-glucopyranoside
  • Rhein-8-O-β-D-glucopyranoside(Rhein-8-glucoside calcium )
  • 2-Anthracenecarboxylicacid, 8-b-D-glucopyranosyl-9,10-dihydro-4,5-dihydroxy-9,10-dioxo-,calciuM salt (1:1)
  • Glucorhein
  • (-)-Syringaresnol-4-O-β-D-apiofuranosyl-(1→2)-β-D-glucopyranoside
CAS:
113443-70-2
MF:
C21H20CaO11
MW:
488.46
Product Categories:
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
Mol File:
113443-70-2.mol
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RHEIN-8-GLUCOSIDE Chemical Properties

solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
powder
color 
Yellow
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RHEIN-8-GLUCOSIDE Usage And Synthesis

Chemical Properties

Yellow crystals, soluble in methanol, ethanol, DMSO and other organic solvents, derived from the rhizome of rhubarb.

Uses

Rhein-8-O-glucoside extracted from rhubarb has anti-tumor, antibacterial and immunosuppressive effects.

Definition

ChEBI: Glucorhein is a member of anthracenes.

Biological Activity

Rhein-8-glucoside calcium, an anthraquinone compound isolated from the EtOH extract of Saussurea lappa root. It is a hPTP1B inhibitor with IC50 of 11.5 μM. It has antibacterial properties.

target

IC50: 11.5 μM (hPTP1B)

RHEIN-8-GLUCOSIDESupplier

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