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4-Nitrocinnamic acid

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4-Nitrocinnamic acid Basic information

Product Name:
4-Nitrocinnamic acid
Synonyms:
  • RARECHEM BK HC P253
  • OTAVA-BB BB7020401717
  • TRANS-3-(3-NITROPHENYL)PROPENOIC ACID
  • TRANS-3-NITROCINNAMIC ACID
  • 3-(3-NITROPHENYL)ACRYLIC ACID
  • AKOS B004090
  • LABOTEST-BB LT00005570
  • (2E)-3-(4-Nitrophenyl)-2-propenoic acid
CAS:
619-89-6
MF:
C9H7NO4
MW:
193.16
EINECS:
210-617-9
Product Categories:
  • Aromatics
  • Aromatics Compounds
  • FINE Chemical & INTERMEDIATES
  • Aromatic Cinnamic Acids, Esters and Derivatives
  • Cinnamic acid
  • Heterocyclic Compounds
Mol File:
619-89-6.mol
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4-Nitrocinnamic acid Chemical Properties

Melting point:
200-202 °C(lit.)
Boiling point:
329.36°C (rough estimate)
Density 
1.4058 (rough estimate)
refractive index 
1.5200 (estimate)
storage temp. 
Sealed in dry,Store in freezer, under -20°C
solubility 
DMSO
form 
Solid
pka
4.07±0.10(Predicted)
color 
Yellow
Water Solubility 
insoluble
InChIKey
XMMRNCHTDONGRJ-ZZXKWVIFSA-N
CAS DataBase Reference
619-89-6(CAS DataBase Reference)
NIST Chemistry Reference
trans-4-Nitrocinnmic acid(619-89-6)
EPA Substance Registry System
2-Propenoic acid, 3-(4-nitrophenyl)- (619-89-6)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
22-24/25
WGK Germany 
3
RTECS 
GE0352000
HazardClass 
IRRITANT
HS Code 
29163990

MSDS

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4-Nitrocinnamic acid Usage And Synthesis

Chemical Properties

Yellow needle-like crystals. Melting point 289°C. Insoluble in water.

Occurrence

The heartwood of Cassia garrettiana.

Uses

4-Nitrocinnamic Acid (cas# 619-89-6) is a compound useful in organic synthesis.

Preparation

Synthesis of 4-nitrocinnamic acid: 4-nitro-trans-cinnamonitrile, concentrated hydrochloric acid and water were heated and refluxed for 8h, and left standing overnight. The precipitate was filtered out, dissolved in hot 30% sodium hydroxide solution, the insoluble matter was filtered off, the filtrate was acidified with 50% sulfuric acid to precipitate precipitation, the crude product was filtered, and recrystallized with ethanol to obtain 4-nitrocinnamic acid.

Biological Activity

4-Nitrocinnamic acid is a photosensitive compound that has inhibitory effects on tyrosinase.

4-Nitrocinnamic acid Preparation Products And Raw materials

Raw materials

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