Recombinant Staphylokinase
Recombinant Staphylokinase Basic information
- Product Name:
- Recombinant Staphylokinase
- Synonyms:
-
- Staphylokinase
- Staphylokise
- CAS:
- 9040-61-3
- MW:
- 0
- Product Categories:
-
- enzyme
- Mol File:
- Mol File
Recombinant Staphylokinase Usage And Synthesis
Uses
Staphylokinase, staphylococcus aureus (SAK) is a fibrin-specific plasminogen activator. Staphylokinase is an efficient, fibrin-selective thrombolytic agent[1].
Description
Staphylokinase Recombinant produced in E.Coli is a non-glycosylated polypeptide chain containing 136 amino acids and having a molecular weight of 16kDa.
The Staphylokinase is purified by proprietary chromatographic techniques.
Background
Staphylokinase (SAK) is a 136-amino acidenzymefrom Staphylococcus aureus. It is positively regulated by the "agr" gene regulator. It activates plasminogen, which in turn can degrade various host proteins during infection.
References
[1] Toul M, et al. Hidden Potential of Highly Efficient and Widely Accessible Thrombolytic Staphylokinase. Stroke. 2022 Oct;53(10):3235-3237. DOI:10.1161/STROKEAHA.122.040219
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