ChemicalBook > Product Catalog > Flavors and fragrances > Synthetic fragrances > Oxygen-containing heterocyclic compounds > Thiazole, thiophene, and pyridine > 4-Hydroxypiperidine
4-Hydroxypiperidine
4-Hydroxypiperidine Basic information
- Product Name:
- 4-Hydroxypiperidine
- Synonyms:
-
- PIPERIDIN-4-OL
- 4-PIPERIDINOL
- 4PPOL
- 4-HYDROXYPIPERIDINE
- HYDROXYPIPERIDINE(4-)
- AURORA KA-1006
- 4-Hydroxypiperidine base
- 4-Hydroxypiperidine, 99+%
- CAS:
- 5382-16-1
- MF:
- C5H11NO
- MW:
- 101.15
- EINECS:
- 226-373-1
- Product Categories:
-
- Building Blocks
- C5 to C7
- Piperidines, Piperidones, Piperazines
- Chemical Synthesis
- Heterocyclic Building Blocks
- Piperidines
- Alcohols and Derivatives
- Amines and Anilines
- Pyrans, Piperidines &Piperazines
- Piperidine
- Heterocyclic Compounds
- NADIFLOXACIN
- Pyrans, Piperidines & Piperazines
- Mol File:
- 5382-16-1.mol
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4-Hydroxypiperidine Chemical Properties
- Melting point:
- 86-90 °C
- Boiling point:
- 108-114 °C/10 mmHg (lit.)
- Density
- 0.9903 (rough estimate)
- vapor pressure
- 13Pa at 25℃
- refractive index
- 1.4400 (estimate)
- Flash point:
- 226 °F
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 14.94±0.20(Predicted)
- color
- Off-White to pale Yellow
- PH
- 11.5-11.7 (H2O)Aqueous solution
- Water Solubility
- soluble
- Sensitive
- Hygroscopic
- BRN
- 102738
- InChIKey
- HDOWRFHMPULYOA-UHFFFAOYSA-N
- LogP
- -0.35 at 25℃
- CAS DataBase Reference
- 5382-16-1(CAS DataBase Reference)
- NIST Chemistry Reference
- 4-Hydroxypiperidine(5382-16-1)
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Safety Information
- Hazard Codes
- Xi,C
- Risk Statements
- 36/37/38-34
- Safety Statements
- 26-36-37/39-45-36/37/39-27
- RIDADR
- 3263
- WGK Germany
- 3
- Hazard Note
- Irritant
- HazardClass
- 8
- PackingGroup
- III
- HS Code
- 29333999
MSDS
- Language:English Provider:4-Hydroxypiperidine
- Language:English Provider:SigmaAldrich
- Language:English Provider:ACROS
- Language:English Provider:ALFA
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4-Hydroxypiperidine Usage And Synthesis
Chemical Properties
yellow to yellow-orange wet solid
Uses
4-Hydroxypiperidine (4-Piperidinol) can be used in the synthesis of a highly potent and selective IP (PGI(2) receptor) agonist. It can also be used in the study of copper-catalyzed N- versus O-arylation.
Uses
4-Hydroxypiperidine is used as a reagent for the synthesis of acridine (A190900) derivatives and fibrinogen receptor antagonists.
General Description
The molecular structure, vibrational spectra, NBO and UV-spectral analysis of 4-Hydroxypiperidine have been studied. The compounds with a substituted 4-piperidinol core have been found to be potent antagonists of the human H(3) receptor.
Flammability and Explosibility
Not classified
4-Hydroxypiperidine Preparation Products And Raw materials
Preparation Products
2-(4-Hydroxypiperidin-1-yl)-6-(trifluoromethyl)pyrimidine-4-carboxamide1-(5-(Hydroxymethyl)pyrimidin-2-yl)piperidin-4-ol1-(4-(Hydroxymethyl)-6-(trifluoromethyl)pyrimidin-2-yl)piperidin-4-olEthyl 2-(4-hydroxypiperidin-1-yl)pyrimidine-5-carboxylate2-(4-Hydroxypiperidin-1-yl)pyrimidine-5-carboxylic acid2-(4-Hydroxypiperidin-1-yl)pyrimidine-5-carboxamideLoperamideEthyl 2-(4-hydroxypiperidin-1-yl)-6-(trifluoromethyl)pyrimidine-4-carboxylate4-Chloro-N-methylpiperidine1-(2-FLUORO-4-NITROPHENYL)PIPERIDIN-4-OL1-(5-aminopyridin-2-yl)piperidin-4-ol4-Bromopiperidine hydrobromide1-[5-NITROPYRIDIN-2-YL]PIPERIDINE-4-OLEbastine
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4-Hydroxypiperidine (5382-16-1)Related Product Information
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