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EPA

Basic information Safety Supplier Related

EPA Basic information

Product Name:
EPA
Synonyms:
  • 5C,8C,11C,14C,17C-EICOSAPENTAENOIC ACID
  • 5,8,11,14,17-EICOSAPENTAENOIC ACID
  • 5Z,8Z,11Z,14Z,17Z-EICOSAPENTAENOIC ACID
  • ALL CIS-5,8,11,14,17-EICOSAPENTAENOIC ACID
  • ALL CIS 5-8-11-14-17 EPA
  • ALL CIS-5,8,11,14,17-ICOSAPENTAENOIC ACID
  • C20:5 (ALL CIS-5,8,11,14,17) ACID
  • C20:5 OMEGA-3
CAS:
73167-03-0
MF:
C20H29O2.Na
MW:
324.44
Product Categories:
  • Lipoxygenase (5-)Unsaturated fatty acids and derivatives
  • LipoxygenaseEnzyme Inhibitors by Enzyme
  • Omega 3 fatty acids and derivativesBiochemicals Found in Plants
  • Arachidonic Acid Cascade
  • Enzyme Inhibitors
  • L to
  • Lipids
  • Polyunsaturated
Mol File:
73167-03-0.mol
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EPA Chemical Properties

Melting point:
−54-−53 °C(lit.)
Density 
0.943 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.4977(lit.)
storage temp. 
-20°C
solubility 
Ethanol: 1.5 mg/ml; Ethanol:PBS(pH 7.2) (1:5): 0.5 mg/ml
form 
waxy solid
color 
white
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Safety Information

Hazard Codes 
C
Risk Statements 
34
Safety Statements 
26-36/37/39-45
RIDADR 
UN 3265 8/PG 3
WGK Germany 
3
8-10-23

MSDS

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EPA Usage And Synthesis

Uses

reduces thromboxane A2 production and platelet aggregation, inhibits 5-lipoxygenase and prevents arteriosclerosis.

Uses

cis-5,8,11,14,17-Eicosapentaenoic acid sodium salt has been used:

  • to study its effect on the pathology of lupus in drug-induced and spontaneous mouse models
  • to pretreat mouse alveolar macrophages to study the effect/relationship between amiodarone and eicosapentaenoic acid (EPA) concerning the cytokine release
  • to examine if pharmacological correction with EPA supplementation might restore autophagic flux and reduce renal lipotoxicity in mice

General Description

Eicosapentaenoic acid (EPA)/timnodonic acid is an omega-3 polyunsaturated fatty acid (PUFA). This long-chain fatty acid is mainly found in fish oil.

Biochem/physiol Actions

Eicosapentaenoic acid (EPA) possesses anti-hyperglycemic, anti-oxidant, anti-hyperlipidemic, and anti-inflammatory properties. It aids in improving vasoreactivity. EPA is capable of suppressing vascular smooth muscle proliferation. It ameliorates pulmonary hypertension by preventing Fyn kinase activity. EPA exhibits a beneficial effect on lipid metabolism. It is used to treat hypercholesterolemia and atherosclerosis.

EPASupplier

3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Email
3bsc@sina.com
Guangzhou Isun Pharmaceutical Co., Ltd
Tel
020-39119399 18927568969
Email
isunpharm@qq.com
Yichang Zhongyitai Trading Co., Ltd.
Tel
0717-6449896 13886658719
Email
root@zhongyitai.com
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Email
info@efebio.com