EPA Chemical Properties

Melting point:

−54-−53 °C(lit.)

Density 

0.943 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.4977(lit.)

storage temp. 

-20°C

solubility 

Ethanol: 1.5 mg/ml; Ethanol:PBS(pH 7.2) (1:5): 0.5 mg/ml

form 

waxy solid

color 

white

Safety Information

Hazard Codes 

C

Risk Statements 

34

Safety Statements 

26-36/37/39-45

RIDADR 

UN 3265 8/PG 3

WGK Germany 

3

F 

8-10-23

MSDS

• Language:English Provider:SigmaAldrich

EPA Usage And Synthesis

Uses

reduces thromboxane A2 production and platelet aggregation, inhibits 5-lipoxygenase and prevents arteriosclerosis.

Uses

cis-5,8,11,14,17-Eicosapentaenoic acid sodium salt has been used:

• to study its effect on the pathology of lupus in drug-induced and spontaneous mouse models
• to pretreat mouse alveolar macrophages to study the effect/relationship between amiodarone and eicosapentaenoic acid (EPA) concerning the cytokine release
• to examine if pharmacological correction with EPA supplementation might restore autophagic flux and reduce renal lipotoxicity in mice

General Description

Eicosapentaenoic acid (EPA)/timnodonic acid is an omega-3 polyunsaturated fatty acid (PUFA). This long-chain fatty acid is mainly found in fish oil.

Biochem/physiol Actions

Eicosapentaenoic acid (EPA) possesses anti-hyperglycemic, anti-oxidant, anti-hyperlipidemic, and anti-inflammatory properties. It aids in improving vasoreactivity. EPA is capable of suppressing vascular smooth muscle proliferation. It ameliorates pulmonary hypertension by preventing Fyn kinase activity. EPA exhibits a beneficial effect on lipid metabolism. It is used to treat hypercholesterolemia and atherosclerosis.

EPA(73167-03-0)Related Product Information

• ALL CIS-5,8,11,14,17-EICOSAPENTAENOIC ACID ETHYL ESTER
• Eicosapentaenoic acid ethyl ester
• EPA
• CIS-5,8,11,14,17-EICOSAPENTAENOIC ACID METHYL ESTER
• EPA
• 15(S)-HYDROPEROXY-(5Z,8Z,11Z,13E,17Z)-EICOSAPENTAENOIC ACID
• 15(S)-HYDROXY-(5Z,8Z,11Z,13E,17Z)-EICOSAPENTAENOIC ACID
• (+/-)-11-HYDROXY-5Z,8Z,12E,14Z,17Z-EICOSAPENTAENOIC ACID
• EPA
• 12R-HYDROXY-5Z,8Z,10E,14Z,17Z-EICOSAPENTAENOIC ACID
• (+/-)-5-HYDROXY-6E,8Z,11Z,14Z,17Z-EICOSAPENTAENOIC ACID
• (+/-)-15-HYDROXY-5Z,8Z,11Z,13E,17Z-EICOSAPENTAENOIC ACID
• (+/-)-12-HYDROXY-5Z,8Z,10E,14Z,17Z-EICOSAPENTAENOIC ACID
• 9S-HYDROXY-5Z,7E,11Z,14Z,17Z-EICOSAPENTAENOIC ACID
• (+/-)-8-HYDROXY-5Z,9E,11Z,14Z,17Z-EICOSAPENTAENOIC ACID
• (+/-)-18-HYDROXY-5Z,8Z,11Z,14Z,16E-EICOSAPENTAENOIC ACID
• (+/-)-9-HYDROXY-5Z,7E,11Z,14Z,17Z-EICOSAPENTAENOIC ACID
• 12S-HYDROPEROXY-5Z,8Z,10E,14Z,17Z-EICOSAPENTAENOIC ACID