EPA
EPA Basic information
- Product Name:
- EPA
- Synonyms:
-
- 5C,8C,11C,14C,17C-EICOSAPENTAENOIC ACID
- 5,8,11,14,17-EICOSAPENTAENOIC ACID
- 5Z,8Z,11Z,14Z,17Z-EICOSAPENTAENOIC ACID
- ALL CIS-5,8,11,14,17-EICOSAPENTAENOIC ACID
- ALL CIS 5-8-11-14-17 EPA
- ALL CIS-5,8,11,14,17-ICOSAPENTAENOIC ACID
- C20:5 (ALL CIS-5,8,11,14,17) ACID
- C20:5 OMEGA-3
- CAS:
- 73167-03-0
- MF:
- C20H29O2.Na
- MW:
- 324.44
- Product Categories:
-
- Lipoxygenase (5-)Unsaturated fatty acids and derivatives
- LipoxygenaseEnzyme Inhibitors by Enzyme
- Omega 3 fatty acids and derivativesBiochemicals Found in Plants
- Arachidonic Acid Cascade
- Enzyme Inhibitors
- L to
- Lipids
- Polyunsaturated
- Mol File:
- 73167-03-0.mol
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EPA Chemical Properties
- Melting point:
- −54-−53 °C(lit.)
- Density
- 0.943 g/mL at 25 °C(lit.)
- refractive index
- n20/D 1.4977(lit.)
- storage temp.
- -20°C
- solubility
- Ethanol: 1.5 mg/ml; Ethanol:PBS(pH 7.2) (1:5): 0.5 mg/ml
- form
- waxy solid
- color
- white
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Safety Information
- Hazard Codes
- C
- Risk Statements
- 34
- Safety Statements
- 26-36/37/39-45
- RIDADR
- UN 3265 8/PG 3
- WGK Germany
- 3
- F
- 8-10-23
MSDS
- Language:English Provider:SigmaAldrich
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EPA Usage And Synthesis
Uses
reduces thromboxane A2 production and platelet aggregation, inhibits 5-lipoxygenase and prevents arteriosclerosis.
Uses
cis-5,8,11,14,17-Eicosapentaenoic acid sodium salt has been used:
- to study its effect on the pathology of lupus in drug-induced and spontaneous mouse models
- to pretreat mouse alveolar macrophages to study the effect/relationship between amiodarone and eicosapentaenoic acid (EPA) concerning the cytokine release
- to examine if pharmacological correction with EPA supplementation might restore autophagic flux and reduce renal lipotoxicity in mice
General Description
Eicosapentaenoic acid (EPA)/timnodonic acid is an omega-3 polyunsaturated fatty acid (PUFA). This long-chain fatty acid is mainly found in fish oil.
Biochem/physiol Actions
Eicosapentaenoic acid (EPA) possesses anti-hyperglycemic, anti-oxidant, anti-hyperlipidemic, and anti-inflammatory properties. It aids in improving vasoreactivity. EPA is capable of suppressing vascular smooth muscle proliferation. It ameliorates pulmonary hypertension by preventing Fyn kinase activity. EPA exhibits a beneficial effect on lipid metabolism. It is used to treat hypercholesterolemia and atherosclerosis.
EPASupplier
3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel
- 821-50328103-801 18930552037
- 3bsc@sina.com
Guangzhou Isun Pharmaceutical Co., Ltd
- Tel
- 020-39119399 18927568969
- isunpharm@qq.com
Yichang Zhongyitai Trading Co., Ltd.
- Tel
- 0717-6449896 13886658719
- root@zhongyitai.com
Sigma-Aldrich
- Tel
- 021-61415566 800-8193336
- orderCN@merckgroup.com
Shanghai EFE Biological Technology Co., Ltd.
- Tel
- 021-65675885 18964387627
- info@efebio.com
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EPA(73167-03-0)Related Product Information
- ALL CIS-5,8,11,14,17-EICOSAPENTAENOIC ACID ETHYL ESTER
- Eicosapentaenoic acid ethyl ester
- EPA
- CIS-5,8,11,14,17-EICOSAPENTAENOIC ACID METHYL ESTER
- EPA
- 15(S)-HYDROPEROXY-(5Z,8Z,11Z,13E,17Z)-EICOSAPENTAENOIC ACID
- 15(S)-HYDROXY-(5Z,8Z,11Z,13E,17Z)-EICOSAPENTAENOIC ACID
- (+/-)-11-HYDROXY-5Z,8Z,12E,14Z,17Z-EICOSAPENTAENOIC ACID
- EPA
- 12R-HYDROXY-5Z,8Z,10E,14Z,17Z-EICOSAPENTAENOIC ACID
- (+/-)-5-HYDROXY-6E,8Z,11Z,14Z,17Z-EICOSAPENTAENOIC ACID
- (+/-)-15-HYDROXY-5Z,8Z,11Z,13E,17Z-EICOSAPENTAENOIC ACID
- (+/-)-12-HYDROXY-5Z,8Z,10E,14Z,17Z-EICOSAPENTAENOIC ACID
- 9S-HYDROXY-5Z,7E,11Z,14Z,17Z-EICOSAPENTAENOIC ACID
- (+/-)-8-HYDROXY-5Z,9E,11Z,14Z,17Z-EICOSAPENTAENOIC ACID
- (+/-)-18-HYDROXY-5Z,8Z,11Z,14Z,16E-EICOSAPENTAENOIC ACID
- (+/-)-9-HYDROXY-5Z,7E,11Z,14Z,17Z-EICOSAPENTAENOIC ACID
- 12S-HYDROPEROXY-5Z,8Z,10E,14Z,17Z-EICOSAPENTAENOIC ACID