2-(Diphenylphosphino)-biphenyl Chemical Properties

Melting point:

80.0 to 86.0 °C

Boiling point:

473.2±24.0 °C(Predicted)

storage temp. 

Inert atmosphere,Room Temperature

form 

Solid

color 

White to Almost white

Water Solubility 

Slightly soluble in water.

CAS DataBase Reference

13885-09-1

Safety Information

HS Code 

2931.90.9051

2-(Diphenylphosphino)-biphenyl Usage And Synthesis

Uses

2-(Diphenylphosphino)biphenyl is used as an organic chemical synthesis intermediate.

Uses

2-(Diphenylphosphino)biphenyl as ligand for suzuki reaction.

Synthesis

General procedure for the synthesis of 2-(diphenylphosphino)-biphenyl from 2-iodobiphenyl and diphenylphosphine: MCM-41-3N-Pd(0) catalyst (21 mg, 0.01 mmol), KOAc (1.5 mmol), and 2-iodobiphenyl (1.0 mmol if solid) were placed in a 20 mL Schlenk tube that had been pre oven-dried. The reaction vessel was evacuated and displaced three times with argon. Subsequently, 2-iodobiphenyl (1.0 mmol, if liquid), diphenylphosphine (1.2 mmol) and DMAc (1 mL) were added via syringe under argon protection. The reaction mixture was stirred at 130°C for 3 hours. After the reaction was completed, the mixture was cooled to room temperature, diluted with CH2Cl2 (20 mL) and filtered.The MCM-41-3N-Pd(0) catalyst was washed with distilled water (2 × 5 mL) and ethanol (2 × 5 mL) for next use. The filtrate was concentrated under vacuum and the residue was purified by fast column chromatography on silica gel to afford the target product 2-(diphenylphosphino)-biphenyl.

References

[1] Organic Letters, 2003, vol. 5, # 13, p. 2315 - 2318
[2] Applied Organometallic Chemistry, 2018, vol. 32, # 8,
[3] Journal of Organometallic Chemistry, 2018, vol. 866, p. 50 - 58

2-(Diphenylphosphino)-biphenyl(13885-09-1)Related Product Information

• 2-(Diphenylphosphino)-2',4',6'-triisopropylbiphenyl
• 2-(Diphenylphosphino)-2'-methylbiphenyl
• 2-(Diphenylphosphino)-2'-methoxybiphenyl
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• 2-(Dicyclohexylphosphino)-3,6-dimethoxy-2'-4'-6'-tri-i-propyl-1,1'-biphenyl, min. 98% BrettPhos
• X-PHOS
• Diphenylphosphine