3,5-Dibenzyloxyacetophenone Chemical Properties

Melting point:

60-62 °C (lit.)

Boiling point:

429.52°C (rough estimate)

Density 

1.1079 (rough estimate)

refractive index 

1.6000 (estimate)

storage temp. 

Sealed in dry,Room Temperature

solubility 

Soluble in dichloromethane, ethyl acetate and methanol

form 

Solid

color 

Off-White to Pale Yellow

InChIKey

KOJXGMJOTRYLBD-UHFFFAOYSA-N

CAS DataBase Reference

28924-21-2(CAS DataBase Reference)

EPA Substance Registry System

Ethanone, 1-[3,5-bis(phenylmethoxy)phenyl]- (28924-21-2)

Safety Information

Hazard Codes 

Xi

Safety Statements 

24/25

WGK Germany 

3

Hazard Note 

Irritant

TSCA 

Yes

HS Code 

29145090

MSDS

• Language:English Provider:3,5-Dibenzyloxyacetophenone
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

3,5-Dibenzyloxyacetophenone Usage And Synthesis

Chemical Properties

beige crystalline powder. 

Uses

3,5-Dibenzyloxyacetophenone is used in the synthesis of enantiomerically pure B-ring modified analogs of (-)-epicatechin gallate.

Uses

The product 3,5-dibenzyloxyacetophenone is widely used as intermediate in the production of a pharmaceutical for treatment of obesity, diabetes, glaucoma, AIDS, HIV infection, antiinflammatory effects, and also in the treatment of disorders which result from leukotriene, tranquilizers, hypotensives, diuretics, and antiglaucoma agents.^[1]

References

[1] Ganapati D. Yadav,  Omprakash V. Badure. “Selective acylation of 1,3-dibenzyloxybenzene to 3,5-dibenzyloxyacetophenone over cesium modified dodecatungstophosphoric acid (DTP) on clay.” Applied Catalysis A: General 348 1 (2008): Pages 16-25.

3,5-Dibenzyloxyacetophenone(28924-21-2)Related Product Information

• 4'-Methylacetophenone
• 3-Nitroacetophenone
• 4'-Hydroxyacetophenone
• Acetophenone
• 2-Bromoacetophenone
• 3,5-Diacetoxyacetophenone
• 4-Nitroacetophenone
• 3',5'-Dimethoxyacetophenone
• 4'-Bromoacetophenone
• 4-Methoxybenzylchloride
• 3,5-Bis(benzyloxy)benzoic acid benzyl ester
• 5-(1-Hydroxy-2-tert-butylamino-ethyl)benzene-1,3-diol
• 1-[3,5-bis(phenylmethoxy)phenyl]-2-bromoethan-1-one
• Terbutaline Impurity 4
• Terbutaline IMpurity B
• Terbutaline IMpurity 8
• N-tert-butyldibenzylamine
• 1-(3,5-DIHYDROXYPHENYL)-2-[(1,1-DIMETHYLETHYL)AMINO]-ETHANONE, HYDROCHLORIDE