4-(CHLOROMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE Chemical Properties

Boiling point:

156-158 °C(lit.)

Density 

1.063 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.434(lit.)

Flash point:

128 °F

storage temp. 

2-8°C

solubility 

Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)

form 

Oil

color 

Colourless

Stability:

Volatile

CAS DataBase Reference

4362-40-7

EPA Substance Registry System

1,3-Dioxolane, 4-(chloromethyl)-2,2-dimethyl- (4362-40-7)

Safety Information

Hazard Codes 

T

Risk Statements 

10-25

Safety Statements 

16-23-26-36/37/39

RIDADR 

UN 1992 3/PG 3

WGK Germany 

3

RTECS 

JH6950000

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS

4-(CHLOROMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE Usage And Synthesis

Chemical Properties

clear colourless to light yellow liquid

Uses

4-Chloromethyl-2,2-dimethyl-1,3-dioxolane may be used in the preparation of 2,2-dimethyl-4-methylene-1,3-dioxolane via dehydrochlorination.

Uses

4-Chloromethyl-2,2-dimethyl-1,3-dioxolane is used in biosynthetic preparations.

Synthesis Reference(s)

Canadian Journal of Chemistry, 44, p. 1331, 1966 DOI: 10.1139/v66-199

General Description

4-Chloromethyl-2,2-dimethyl-1,3-dioxolane is a ketal that can be synthesized by the reaction of 3-chloro-propane-1,2-diol (3-MCPD) with acetone in the presence of p-toluene sulfonic acid.

4-(CHLOROMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE(4362-40-7)Related Product Information

• (R)-(+)-4-CHLOROMETHYL-2,2-DIMETHYL-1,3-DIOXOLANE,(R)-4-(CHLOROMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE
• 4-(CHLOROMETHYL)-2-METHYL-2-PHENYL-1,3-DIOXOLANE
• 3-CHLORO-3-DEOXY-1,2:5,6-DIISOPROPYLIDENE-ALPHA-D-GLUCOFURANOSE
• 4-CHLOROMETHYL-2-ISOBUTYL-2-METHYL-[1,3]DIOXOLANE
• ALPHA-CHLORO-2,3,5,6-DIISOPROPYLIDENE-D-MANNOSE
• 3-CHLORO-3-DEOXY-1:2,5:6-DIISOPROPYLIDENE-D-GLUCOPYRANOSE
• (S)-(-)-4-Chloromethyl-2,2-dimethyl-1,3-dioxolane
• 4-(CHLOROMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE
• 2-(CHLOROMETHYL)-1,4-DIOXASPIRO[4.11]HEXADECANE
• 2-(CHLOROMETHYL)-1,4-DIOXASPIRO[4.4]NONANE