Aprepitant-d4
Aprepitant-d4 Basic information
- Product Name:
- Aprepitant-d4
- Synonyms:
-
- Aprepitant-d4
- 5-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(2,3,5,6-tetradeuterio-4-fluorophenyl)morpholin-4-yl]methyl]-1,2-dihydro-1,2,4-triazol-3-one
- 5-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl-2,3,5,6-d4)morpholino)methyl)-2,4-dihydro-3H-1,2,4-triazol-3-one
- [2H4]-Aprepitant
- Aprepitant D4Q: What is Aprepitant D4 Q: What is the CAS Number of Aprepitant D4 Q: What is the storage condition of Aprepitant D4 Q: What are the applications of Aprepitant D4
- CAS:
- 1133387-60-6
- MF:
- C23H17D4F7N4O3
- MW:
- 538.451309512
- Product Categories:
-
- Chiral Reagents, Heterocycles, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals
- Mol File:
- 1133387-60-6.mol
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Aprepitant-d4 Chemical Properties
- Melting point:
- 242-244°C
- storage temp.
- -20°C Freezer
- solubility
- DMSO (Slightly), Methanol (Slightly, Sonicated)
- form
- Solid
- color
- White to Off-White
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Aprepitant-d4 Usage And Synthesis
Uses
Aprepitant-d4 is a labeled analogue of Aprepitant (A729800), A novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Aprepitant-d4 is a potential treatment for chemotherapy induced nausea and vomiting.
Aprepitant-d4Supplier
J & K SCIENTIFIC LTD.
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- 010-82848833 400-666-7788
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Shanghai TaoSu Biochemical Technology Co., Ltd.
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- 021-33632979
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Cato Research Chemicals Inc.
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- 020-81960175
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ChemStrong Scientific Co.,Ltd
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- 0755-0755-66853366 13670046396
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Shenzhen SUNGENING Bio-Medical Co., Ltd.
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- 0755-28967200 13631290199
- wxf@sungening.com