2-Amino-4-methoxy-6-methylpyrimidine Chemical Properties

Melting point:

156-158 °C (lit.)

Boiling point:

255.11°C (rough estimate)

Density 

1.2081 (rough estimate)

refractive index 

1.6500 (estimate)

solubility 

methanol: soluble1%, clear to very slightly hazy, colorless to yellow

form 

powder to crystal

pka

6.38±0.10(Predicted)

color 

White to Almost white

BRN 

121733

CAS DataBase Reference

7749-47-5(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi,Xn

Risk Statements 

36/37/38-21/22

Safety Statements 

26-36-37/39

WGK Germany 

3

F 

8

Hazard Note 

Irritant

HS Code 

29335990

MSDS

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• Language:English Provider:ACROS
• Language:English Provider:ALFA

2-Amino-4-methoxy-6-methylpyrimidine Usage And Synthesis

Chemical Properties

white to pinkish or light beige

Uses

2-Amino-4-methoxy-6-methylpyrimidine may be employed as nucleophile to investigate the regioselective introduction of some nucleophiles at the secondary position of Baylis-Hillman adducts. It may be used in the preparation of 2-amino-4-methoxy-6-methylpyrimidin-1-ium picrate.

General Description

2-Amino-4-methoxy-6-methylpyrimidine (AMMP) is a pyrimidine derivative. It acts as electron donor and forms charge transfer complexes with iodine (σ-electron acceptor). The FTIR and FT-Raman spectra of 2-amino-4-methoxy-6-methylpyrimidine have been recorded to evaluate the energy, structural and thermodynamical parameters. Molecules of AMMP exhibit space group of Pnma and are joined by two N-H…N hydrogen bonds.

Purification Methods

Recrystallise it from H2O. The picrate has m 220-221o(dec). [Baker et al. J Am pKEst ~ Chem Soc 69 3072, 3075 1947, Sirakawa et al. Yakugaku Zasshi 73 598 1953, Backer & Grevenstuk Recl Trav Chim, Pays-Bas 61 291 1942, Beilstein 25 III/IV 3385.]

2-Amino-4-methoxy-6-methylpyrimidine(7749-47-5)Related Product Information

• N,N-Dimethyl-1,4-phenylenediamine
• 2-Amino-4,6-dimethoxypyrimidine
• Pirimiphos-methyl
• 5-METHYLCYTOSINE
• Tris(hydroxymethyl)aminomethane
• Lithium bis(trimethylsilyl)amide
• ALTRENOGEST
• 4-Methylpyrimidine
• 2-Methoxyethanol
• Glycine
• 4-Amino-6-methoxypyrimidine
• PIRIMICARB-DESMETHYL
• Epirizole
• Pirimicarb
• 2-Amino-4-methoxy-6-methylpyrimidine
• AMINO ACIDS
• Methoxy
• N-ETHYL-4-(4-METHOXYPHENOXY)-6-(TRIFLUOROMETHYL)-2-PYRIMIDINAMINE