2-Aminobenzotrifluoride Chemical Properties

Melting point:

34 °C(lit.)

Boiling point:

170-173 °C(lit.)

Density 

1.282 g/mL at 25 °C(lit.)

vapor pressure 

2.1-12.1hPa at 20-50℃

refractive index 

n20/D 1.481(lit.)

Flash point:

131 °F

storage temp. 

Store below +30°C.

solubility 

4g/l

form 

Liquid

pka

1.10±0.10(Predicted)

Specific Gravity

1.282

color 

Clear colorless to light amber

Water Solubility 

4 g/L (20 ºC)

BRN 

879494

LogP

2.32 at 23℃ and pH7

CAS DataBase Reference

88-17-5(CAS DataBase Reference)

NIST Chemistry Reference

Benzenamine, 2-(trifluoromethyl)-(88-17-5)

EPA Substance Registry System

o-(Trifluoromethyl)aniline (88-17-5)

Safety Information

Hazard Codes 

T,Xi,Xn,F

Risk Statements 

10-23/24/25-33-36/37/38-22-20/21/22

Safety Statements 

36/37/39-45-37/39-26-16-36

RIDADR 

UN 2942 6.1/PG 3

WGK Germany 

1

RTECS 

XU9210000

Hazard Note 

Toxic/Irritant

TSCA 

Yes

HazardClass 

6.1

PackingGroup 

III

HS Code 

29214300

MSDS

• Language:English Provider:2-(Trifluoromethyl)aniline
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

2-Aminobenzotrifluoride Usage And Synthesis

Chemical Properties

clear colorless to light amber liquid

Uses

o-Aminobenzotrifluoride-d2 is a 4-substituted aniline derivative that exerts special hematotoxicity on red blood cells and induce leukocytosis. o-Aminobenzotrifluoride-d2 is a thiohydrazides used as an antibacterial remedy for Chlamydial infection treatment at chronic stages of infections.

General Description

A colorless liquid with a fishlike odor. Insoluble in water and denser than water. Contact may irritate skin, eyes and mucous membranes. May be toxic by ingestion. Used to make other chemicals.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

2-Aminobenzotrifluoride is a halogenated amine. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.

Health Hazard

TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

Fire Hazard

Combustible material: may burn but does not ignite readily. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form.

2-Aminobenzotrifluoride(88-17-5)Related Product Information

• 4-Bromobenzotrifluoride
• o-Toluidine
• Benzotrifluoride
• o-Xylene
• 1,4-Bis(trifluoromethyl)-benzene
• 2,3-DIAMINOTOLUENE
• Aniline
• 2-(Trifluoromethoxy)aniline
• 2,5-Bis(trifluoromethyl)aniline
• 2-(Trifluoromethyl)benzoic acid
• 4-(Trifluoromethoxy)aniline
• 3-Fluorobenzotrifluoride
• N,N-Dimethyl-p-toluidine
• 3,3',5,5'-Tetramethylbenzidine dihydrochloride
• 3-Aminobenzotrifluoride;3-(Trifluoromethyl)aniline
• 2-Fluoroaniline
• 2-Methylbenzotrifluoride
• N,N-Dimethylaniline