Chebulic Acid
Chebulic Acid Basic information
- Product Name:
- Chebulic Acid
- Synonyms:
-
- (2S)-2-[(3S)-3,4-Dihydro-3α-carboxy-5,6,7-trihydroxy-1-oxo-1H-2-benzopyran-4β-yl]butanedioic acid
- Butanedioic acid,[(3S,4S)-3-carboxy-3,4-dihydro-5,6,7-trihydroxy-1-oxo-1H-2-benzopyran-4-yl]-,(2S)-
- Chebulic acid
- Split acid
- CHEBULIC ACID(SH)
- (2S)-[(3S,4S)-3-Carboxy-3,4-dihydro-5,6,7-trihydroxy-1-oxo-1H-2-benzopyran-4-yl]butanedioic acid
- (S)-2-((3S,4S)-3-Carboxy-5,6,7-trihydroxy-1-oxoisochroman-4-yl)succinic acid
- (-)-Chebulic acid
- CAS:
- 23725-05-5
- MF:
- C14H12O11
- MW:
- 356.24
- Mol File:
- 23725-05-5.mol
Chebulic Acid Chemical Properties
- Boiling point:
- 755.9±60.0 °C(Predicted)
- Density
- 1.882
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- Powder
- pka
- 2.60±0.40(Predicted)
Chebulic Acid Usage And Synthesis
Description
Chebulic acid is a phenolic compound isolated from the ripe fruits of Terminalia chebula. This compound possesses an isomer, neochebulic acid. Chebulic acid is a component of transformed ellagitannins such as chebulagic acid or chebulinic acid.
Chebulic acid (CA) isolated from T. chebula, which has been reported for treating asthma, as a potent anti-oxidant resources. Exposure to ambient urban particulate matter (UPM) considered as a risk for cardiopulmonary vascular dysfunction.
Bioactivities
Chebulinic acid showed many bioactivities including inhibition of cancer cell growth, inhibiting the contractile responses of cardiovascular muscles, anti-fungal, anti-bacterial activities etc. In-vitro anti-cancer activity of Chebulinic acid on Colon adenocarcinoma HT-29 cancer cell lines by using MTT cell growth inhibition assay was stuied. The maximum percentage inhibition of cancer cell lines for Chebulinic acid was found to be 41.2% at a dose of 200µg/ml. Chebulinic acid extraction from Terminalia chebula plays a vital role in medicine, biotechnology and various pharmacological activities.
Uses
Chebulic acid can be used for the polypharmacology of metabolites of medicinal plants to target SARS-CoV-2. It can also be used as a therapeutic agent to prevent insulin sensitivity and oxidative stress induced dysfunction of beta cells for diabetes.
target
VEGFR | ROS
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Chebulic Acid(23725-05-5)Related Product Information
- Gallic acid
- 3,3'-di-O-methylellagic acid
- (4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one
- 2alpha,19alpha,23-Trihydroxyoleanolic acid
- Chebulinic acid
- Hydroxytyrosol Acetate
- Hydroxytyrosol
- chebulagic acid
- 3,4-Dimethoxybenzoic acid
- 10-Gingerol
- Ellagic acid
- Neochebulagic acid
- 3,4-Dimethoxybenzyl alcohol
- GALLIC ACID ISOAMYL ESTER
- (R)-2-Benzylsuccinic acid
- Chebulic Acid
- 3-(4-HYDROXYPHENYL)-2-METHOXYPROPANOIC ACID