4-[2-(1,3-Benzodioxol-5-yl)-1-methylethyl]-4,5-dimethoxy-2-(2-propenyl)-2,5-cyclohexadien-1-one Chemical Properties

Boiling point:

505.2±50.0 °C(Predicted)

Density 

1.18±0.1 g/cm3(Predicted)

4-[2-(1,3-Benzodioxol-5-yl)-1-methylethyl]-4,5-dimethoxy-2-(2-propenyl)-2,5-cyclohexadien-1-one Usage And Synthesis

Uses

Isodihydrofutoquinol B (compound 9), an active compound, can be isolated from the stems of Piper kadsura (Choisy) Ohwi. Isodihydrofutoquinol B has A neuroprotective effect on Aβ25-35-induced PC12 cell damage with E50 values of 3.06-29.3μM[1].

References

[1] Chen H, et al. Neolignans and amide alkaloids from the stems of Piper kadsura and their neuroprotective activity. Phytochemistry. 2022 Nov;203:113336. DOI:10.1016/j.phytochem.2022.113336
[2] Prasad A K, et al. Lignans and neolignans from stems and fruits of Piper wightii[J]. Tetrahedron, 1994, 50(7): 2231-2240.

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