N-DESMETHYL IMATINIB Chemical Properties

Melting point:

180 - 190°C

Density 

1.248±0.06 g/cm3(Predicted)

storage temp. 

-20°C Freezer

solubility 

Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)

pka

13.20±0.70(Predicted)

form 

Solid

color 

Off-White to Light Yellow

N-DESMETHYL IMATINIB Usage And Synthesis

Uses

Gleevec N-4-((4-Methylpiperazin-1-yl)methyl)benzaldehyde is an impurity of Gleevec (G407000), a tyrosine kinase inhibitor which is highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL).

Uses

N-Desmethyl Imatinib (Imatinib EP Impurity C) is a metabolite of Gleevec, a tyrosine kinase inhibitor which is highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL). It is a COVID19-related research product.

N-DESMETHYL IMATINIB(1356565-46-2)Related Product Information

• Imatinib
• IMatinib DiPiperidine IMpurity
• Imatinib impurity 31
• Imatinib (Pyridine)-N-oxide
• N-(3-GUANIDINO-4-METHYLPHENYL)-4-(METHYLPIPERAZINE-1-YL-METHYL)BENZAMIDE
• iMatinib related substance B
• Imatinib (Piperidine)-N-oxide
• 4-(4-Methylpiperazin-1-ylmethyl)benzoic acid
• 1,4-Bis-[4-[4-Methyl-3-[[4-(pyridin-3-yl)pyriMidin-2-yl]aMino]phenyl]carbaMoyl]benzylpiperazine
• N-Desmethyl Imatinib
• Guanidine, N-(2-methyl-3-nitrophenyl)-
• IMatinib Para-diaMinoMethylbenzene
• Imatinib Meta-methyl-piperazine Impurity
• N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine
• 1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one
• 3-Acetylpyridine
• iMatinib related substance C
• Benzamide, 4-(dichloromethyl)-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-