ChemicalBook > Product Catalog > Analytical Chemistry > Standard > Pharmaceutical Impurity Reference Standards > 4-[N-(2,4-DIAMINO-6-PTERIDINYLMETHYL)-N-METHYLAMINO] BENZOIC ACID
4-[N-(2,4-DIAMINO-6-PTERIDINYLMETHYL)-N-METHYLAMINO] BENZOIC ACID
4-[N-(2,4-DIAMINO-6-PTERIDINYLMETHYL)-N-METHYLAMINO] BENZOIC ACID Basic information
- Product Name:
- 4-[N-(2,4-DIAMINO-6-PTERIDINYLMETHYL)-N-METHYLAMINO] BENZOIC ACID
- Synonyms:
-
- 2,4-Diamino-N(10)-methylpteroic acid
- 4-(((2,4-Diamino-6-pteridinyl)methyl)methylamino)benzoic acid
- Deoxyaminopteroic acid
- N-10-Methyl-4-deoxy-4-aminopteroate
- Nsc 131463
- DAMPA
- p-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoic acid
- 4-[N-[(2,4-DiaMinopyriMido[4,5-b]pyrazin-6-yl)Methyl]-N- MethylaMino]benzoic Acid
- CAS:
- 19741-14-1
- MF:
- C15H15N7O2
- MW:
- 325.33
- Product Categories:
-
- Bases & Related Reagents
- Drug Analogues
- Heterocycles
- Intermediates & Fine Chemicals
- Nucleotides
- Pharmaceuticals
- API
- Mol File:
- 19741-14-1.mol
More
Less
4-[N-(2,4-DIAMINO-6-PTERIDINYLMETHYL)-N-METHYLAMINO] BENZOIC ACID Chemical Properties
- Melting point:
- 255 °C (dec.)(lit.)
- Boiling point:
- 689.3±65.0 °C(Predicted)
- Density
- 1.532
- storage temp.
- 2-8°C(protect from light)
- solubility
- Aqueous Base, DMSO
- pka
- 4.63±0.10(Predicted)
- form
- Solid
- color
- Dark Yellow to Very Dark Brown
- Stability:
- Hygroscopic
- Major Application
- pharmaceutical (small molecule)
- InChI
- 1S/C15H15N7O2/c1-22(10-4-2-8(3-5-10)14(23)24)7-9-6-18-13-11(19-9)12(16)20-15(17)21-13/h2-6H,7H2,1H3,(H,23,24)(H4,16,17,18,20,21)
- InChIKey
- LWCXZSDKANNOAR-UHFFFAOYSA-N
- SMILES
- N(Cc2nc3c(nc(nc3N)N)nc2)(C)c1ccc(cc1)C(=O)O
- CAS DataBase Reference
- 19741-14-1
More
Less
More
Less
4-[N-(2,4-DIAMINO-6-PTERIDINYLMETHYL)-N-METHYLAMINO] BENZOIC ACID Usage And Synthesis
Chemical Properties
Brownish Yellow to Orange Solid
Uses
DAMPA is a Methotrexate (M260675) analog (1). DAMPA is an antitumor agent (2).
in vivo
Methotrexate metabolite (8.6-10.1 mg/kg, 200 mg/m2, i.v., 15 minutes) has pharmacokinetic properties of rapid clearance and extensive metabolism in adult male Rhesus monkeys (Macaca mulatta) (8.0-15.9 kg), with an average clearance rate of 1.9 l/kg/h and an average terminal half-life of 51 minutes[1].
4-[N-(2,4-DIAMINO-6-PTERIDINYLMETHYL)-N-METHYLAMINO] BENZOIC ACIDSupplier
Wuhan Xinsengyang Biotechnology Co., Ltd Gold
- Tel
- 18402740988 18402740988
- 3879363529@qq.com
J & K SCIENTIFIC LTD.
- Tel
- 18210857532; 18210857532
- jkinfo@jkchemical.com
Adamas Reagent, Ltd.
- Tel
- 400-6009262 16621234537
- chenyj@titansci.com
Nanjing Chemlin Chemical Co., Ltd
- Tel
- 025-83697070 13913916777;
- info@chemlin.com.cn
Chemsky（shanghai）International Co.,Ltd.
- Tel
- 021-50135380
- shchemsky@sina.com
More
Less
4-[N-(2,4-DIAMINO-6-PTERIDINYLMETHYL)-N-METHYLAMINO] BENZOIC ACID(19741-14-1)Related Product Information
- Methotrexate γ-Methyl Ester
- Methotrexate
- Aminopterin
- Methotrexate α-Methyl Ester
- Methotrexate impurity
- N-(p-Aminobenzoyl)glutamic acid
- 2,4-DIAMINO-6-(HYDROXYMETHYL)PTERIDINE
- L-Glutamic acid, N-[N-[N-[N-[4-[[(2, 4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-.gamma.-gluta myl]-L-.gamma.-glutamyl]-L-.gamma.-glutamyl]-
- Folic Acid Related Compound A/Calcium Formyltetrahydrofolate
- L-Glutamic acid der.
- 7-HYDROXY METHOTREXATE
- 4-[N-(2,4-DIAMINO-6-PTERIDINYLMETHYL)-N-METHYLAMINO] BENZOIC ACID
- 4-Dimethylaminobenzoic acid
- 6-Methyl-2,4-pteridinediamine
- 4-(N-[2,4-DIAMINO-6-PTERIDINYLMETHYL]-AMINO)BENZOIC ACID SODIUM SALT
- 2,4-Diaminopteridine
- 4-Pteridinamine (9CI)
- 4-[N-(2,4-DIAMINO-6-PTERIDINYLMETHYL)-N-METHYLAMINO]BENZOIC ACID HEMIHYDROCHLORIDE HYDRATE