4-Amino-2-chloropyridine Chemical Properties

Melting point:

90-94 °C(lit.)

Boiling point:

153°C 5mm

Density 

1.2417 (rough estimate)

refractive index 

1.5110 (estimate)

Flash point:

153°C/5mm

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

DMSO (Slightly), Methanol (Slightly)

pka

4.73±0.30(Predicted)

form 

Crystalline Powder

color 

Light yellow

Water Solubility 

Slightly soluble in water.

BRN 

108671

InChIKey

BLBDTBCGPHPIJK-UHFFFAOYSA-N

CAS DataBase Reference

14432-12-3(CAS DataBase Reference)

NIST Chemistry Reference

4-Amino-2-chloropyridine(14432-12-3)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36-37/39-36/37/39

RIDADR 

2811

WGK Germany 

3

HazardClass 

IRRITANT

HS Code 

29333999

MSDS

• Language:English Provider:2-Chloro-4-pyridinamine
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

4-Amino-2-chloropyridine Usage And Synthesis

Description

4-Amino-2-chloropyridine is an important pharmaceutical and pesticide intermediate. It can synthesize N-(2-chloro-4-pyridyl)urea regulators that promote plant growth. It is also a key substance in the synthesis of KT-30 (Forchlorfenuron, IUPAC name N-(2-chloro-4-pyridyl)-N'-phenylurea). KT-30 is a highly active cytokinin, which has the biological activity of promoting tissue growth, promoting bud development and green preservation; it has an effect of increasing yield on apple, pear, grape, peach and other fruit crops.
4-Amino-2-chloropyridine itself can also be used as a pesticide alone, and has high activity against various pathogens such as rust, powdery mildew, rice blast, and apple downy mildew. 4-Amino-2-chloropyridine and its pharmaceutical and pesticide intermediates have the advantages of high biological activity, low toxicity, long-lasting period and easy degradation in the environment, so they have broad application prospects in agricultural production.

Chemical Properties

White powder.

Uses

An aminopyridine derivative with potential herbicidal activity.

Uses

4-Amino-2-chloropyridine may be used in the preparation of:

• 3-deazacytosine
• 7-substituted 1-alky-1,4-dihydro-4-oxo-1,6-naphthyridine-3-carboxylic acids
• 1,6-naphthyridines

Definition

ChEBI: 4-Amino-2-chloropyridine is an aminopyridine.

General Description

4-Amino-2-chloropyridine is a chloroaminoheterocyclic compound. It readily undergoes Suzuki-Miyaura coupling with phenylboronic acid.

4-Amino-2-chloropyridine(14432-12-3)Related Product Information

• ALTRENOGEST
• 4-Aminopyridine
• 3-Aminopyridine
• 4-Amino-2-chlorobenzonitrile
• 4-Amino-2-chlorobenzoic acid
• 2-Chloro-4-bromopyridine
• 2-Chloro-4-iodopyridine
• 2-Aminophenol
• 2,6-Diaminopyridine
• Tris(hydroxymethyl)aminomethane
• 2-Aminopyridine
• 2-Chloro-4-fluoropyridine
• 4-Dimethylaminopyridine
• 6-Aminocaproic acid
• Glycine
• 2-Chloropyridine
• Difluorochloromethane
• 4-AMINO-3-CHLOROPYRIDINE