α,4'-Dihydroxy-3'-methoxypropiophenone Chemical Properties

form 

Solid

color 

Light yellow to brown

LogP

0.622 (est)

α,4'-Dihydroxy-3'-methoxypropiophenone Usage And Synthesis

Uses

β-Hydroxypropiovanillone, a natural compound, shows significant concentration-dependent inhibitory effects on α-glucosidase with an IC50 of 257.8 μg/mL[1].

References

[1] Lv Q , et al. Dihydrochalcone-derived polyphenols from tea crab apple (Malus hupehensis) and their inhibitory effects on α-glucosidase in vitro. Food Funct. 2019;10(5):2881-2887. DOI:10.1039/c9fo00229d
[2] Higuchi Y, et al. Bacterial Catabolism of β-Hydroxypropiovanillone and β-Hydroxypropiosyringone Produced in the Reductive Cleavage of Arylglycerol-β-Aryl Ether in Lignin. Appl Environ Microbiol. 2018;84(7):e02670-17. Published 2018 Mar 19. DOI:10.1128/AEM.02670-17
[3] Higuchi Y, et al. Discovery of novel enzyme genes involved in the conversion of an arylglycerol-β-aryl ether metabolite and their use in generating a metabolic pathway for lignin valorization. Metab Eng. 2019;55:258-267. DOI:10.1016/j.ymben.2019.08.002

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