(3β,16E)-16,17,18,19-Tetradehydro-17-methoxycorynan-16-carboxylic acid methyl ester
(3β,16E)-16,17,18,19-Tetradehydro-17-methoxycorynan-16-carboxylic acid methyl ester Basic information
- Product Name:
- (3β,16E)-16,17,18,19-Tetradehydro-17-methoxycorynan-16-carboxylic acid methyl ester
- Synonyms:
-
- (3β,16E)-16,17,18,19-Tetradehydro-17-methoxycorynan-16-carboxylic acid methyl ester
- 18,19-Didehydrohirsutine
- Methyl (E)-2-[(2S,3R,12bR)-3-Ethenyl-1,2,3,4,6,7,12,12B-Octahydroindolo[3,2-h]Quinolizin-2-Yl]-3-Methoxyprop-2-Enoate
- Δ18-Hirsutine
- (3-beta,16E)-16,17,18,19-Tetradehydro-17-methoxy-corynan-16-carboxylic acid methyl ester
- Corynan-16-carboxylic acid, 16,17,18,19-tetradehydro-17-methoxy-, methyl ester, (3-beta,16E)-
- Corynan-16-carboxylic acid, 16,17,18,19-tetrahydro-17-methoxy-, methyl ester, (3beta,16E)-
- delta(Sup 18)-hirsutine
- CAS:
- 35467-43-7
- MF:
- C22H26N2O3
- MW:
- 366.46
- Mol File:
- 35467-43-7.mol
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(3β,16E)-16,17,18,19-Tetradehydro-17-methoxycorynan-16-carboxylic acid methyl ester Chemical Properties
- Boiling point:
- 533.2±50.0 °C(Predicted)
- Density
- 1.22±0.1 g/cm3(Predicted)
- solubility
- DMSO: soluble
- form
- A solid
- pka
- 18.03±0.60(Predicted)
- color
- Off-white to yellow
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(3β,16E)-16,17,18,19-Tetradehydro-17-methoxycorynan-16-carboxylic acid methyl ester Usage And Synthesis
Chemical Properties
White crystals, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Uncaria rhynchophylla (Miq.) Miq. ex Havil.
Uses
Hirsuteine can be used for antihypertensive.
Definition
ChEBI: Hirsuteine is an alkaloid.
Biological Activity
Hirsuteine is an indole alkaloid extracted from Uncaria. It noncompetitively antagonizes nicotine-mediated dopamine release by blocking ion penetration through the nicotinic receptor channel complex.
(3β,16E)-16,17,18,19-Tetradehydro-17-methoxycorynan-16-carboxylic acid methyl esterSupplier
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