6-Amino-2,2-dimethyl-2H-pyrido[3,2-B][1,4]oxazin-3(4H)-one Chemical Properties

Boiling point:

420.3±45.0 °C(Predicted)

Density 

1.256

Flash point:

208

storage temp. 

2-8°C(protect from light)

pka

10.79±0.40(Predicted)

form 

solid

form 

solid

InChI

InChI=1S/C9H11N3O2/c1-9(2)8(13)12-7-5(14-9)3-4-6(10)11-7/h3-4H,1-2H3,(H3,10,11,12,13)

InChIKey

HSYOWUOUDXDSMC-UHFFFAOYSA-N

SMILES

O1C(C)(C)C(=O)NC2=NC(N)=CC=C12

6-Amino-2,2-dimethyl-2H-pyrido[3,2-B][1,4]oxazin-3(4H)-one Usage And Synthesis

Uses

6-Amino-2,2-dimethyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one is a useful intermediate for the preparation of protein kinase inhibitors.

Application

6-amino-2,2-dimethyl-2h-pyrido[3,2-b][1,4]oxazin-3(4h)-one is the key intermediate of Fostamatinib, which is a medication approved by the U.S. Food and Drug Administration since 2018 for the treatment of chronic immune thrombocytopenia (ITP).

6-Amino-2,2-dimethyl-2H-pyrido[3,2-B][1,4]oxazin-3(4H)-one(1002726-62-6)Related Product Information

• 2,2-dimethyl-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one
• 5-ethoxypyridin-2-amine
• 6-AMINO-2-METHYL-2H-PYRIDO[3,2-B][1,4]OXAZIN-3(4H)-ONE
• 6-amino-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one
• 2,2-DIMETHYL-6-NITRO-2H-PYRIDO[3,2-B][1,4]OXAZIN-3(4H)-ONE
• 6-AMINO-2,2-DIMETHYL-2H-PYRIDO[3,2-B][1,4]OXAZIN-3(4H)-ONE