ChemicalBook > Product Catalog > Organic Chemistry > Nitrogen Compounds > 1-(4-Amino-2-methylbenzoyl)-7-chloro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one
1-(4-Amino-2-methylbenzoyl)-7-chloro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one
1-(4-Amino-2-methylbenzoyl)-7-chloro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one Basic information
- Product Name:
- 1-(4-Amino-2-methylbenzoyl)-7-chloro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one
- Synonyms:
-
- 1-(4-Amino-2-methylbenzoyl)-7-chloro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one
- 5H-1-Benzazepin-5-one, 1-(4-aMino-2-Methylbenzoyl)-7-chloro-1,2,3,4-tetrahydro-
- 1,2,3,4-Tetrahydro-1-(4-amino-2-methylbenzoyl)-7-chloro-5H-1-benzazepin-5-one
- 1-(4-Amino-2-methylbenzoyl)-7-chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one
- Tolvaptan Impurity 10
- 1-(4-aMino-2-Methylbenzoyl)-7-chloro-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one
- 1-(4-Amino-2-Methylbenzoyl)-7-Chloro-1,2,3,4-Tetrahydro-5H-1-benzazepine-5-One
- 1-(4-amino-2-methylbenzoyl)-7-chloro-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one
- CAS:
- 137977-97-0
- MF:
- C18H17ClN2O2
- MW:
- 328.79
- EINECS:
- 1592732-453-0
- Product Categories:
-
- Pharmaceutical Intermediates
- 137977-97-0
- Mol File:
- 137977-97-0.mol
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1-(4-Amino-2-methylbenzoyl)-7-chloro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one Chemical Properties
- Melting point:
- 186-189°C
- Boiling point:
- 565.4±50.0 °C(Predicted)
- Density
- 1.320
- storage temp.
- -20°C Freezer
- solubility
- DMSO (Slightly), Methanol (Slightly)
- pka
- 2.28±0.10(Predicted)
- form
- Solid
- color
- Off-White to Pale Yellow
- InChI
- InChI=1S/C18H17ClN2O2/c1-11-9-13(20)5-6-14(11)18(23)21-8-2-3-17(22)15-10-12(19)4-7-16(15)21/h4-7,9-10H,2-3,8,20H2,1H3
- InChIKey
- FLJCJPKXJWRZJB-UHFFFAOYSA-N
- SMILES
- N1(C(=O)C2=CC=C(N)C=C2C)C2=CC=C(Cl)C=C2C(=O)CCC1
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1-(4-Amino-2-methylbenzoyl)-7-chloro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one Usage And Synthesis
Uses
1,2,3,4-Tetrahydro-1-(4-amino-2-methylbenzoyl)-7-chloro-5H-1-benzazepin-5-one is an intermediate used in the synthetic preparation of Tolvaptan (T536650), a selective nonpeptide arginine vasopressin V2 receptor antagonist.
Uses
1-(4-Amino-2-methylbenzoyl)-7-chloro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one is an intermediate used in the synthetic preparation of Tolvaptan (T536650), a selective nonpeptide arginine vasopressin V 2 receptor antagonist.
1-(4-Amino-2-methylbenzoyl)-7-chloro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-oneSupplier
Enki Biopharmaceuticals(Shanghai) Limited Gold
- Tel
- 021-57680965 13916707528
- yusu@enkibiopharma.com
Jiangxi Jinfeng Pharmaceutical Co., Ltd Gold
- Tel
- 793-5181188 18170363299
- yangyuening@jxjfpharma.com
Suzhou Junye Biopharmaceutical Technology Co., Ltd Gold
- Tel
- 0512-53662086-8001 18913766772
- wangli@jyk-biotech.com
J & K SCIENTIFIC LTD.
- Tel
- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
Chembest Research Laboratories Limited
- Tel
- +86-21-20908456
- sales@BioChemBest.com
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1-(4-Amino-2-methylbenzoyl)-7-chloro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one(137977-97-0)Related Product Information
- Tolvaptan Impurity 11
- Tolvaptan Impurity 26
- 7-Chloro-1,2,3,4-tetrahydrobenzo(b)azepin-5-one
- 5-Dehydro Tolvaptan
- 7-Chloro-1,2,3,4-tetrahydro-1-(2-methyl-4-nitrobenzoyl)-5H-1-benzazepin-5-one
- Tolvaptan Impurity 3 (DM-4104)
- Tolvaptan Impurity 30
- 7-Chloro-1,2,3,4-tetrahydro-1-[(4-methylphenyl)sulfonyl]-5H-1-benzazepin-5-one
- 2-Methyl-4-nitrobenzoic acid
- Tolvaptan Impurity 4 (DM-4105)
- Ethyl 7-Chloro-5-oxo-1-toxyl-2,3,4,5,-tetrahydro-1H-benzo[b]azepine-4-carboxylate
- 5-Chloro-2-[(4-ethoxy-4-oxobutyl)[(4-methylphenyl)sulfonyl]amino]benzoic acid methyl ester
- Tolvaptan Impurity 21
- Tolvaptan Impurity 18
- Tolvaptan Impurity 13
- Tolvaptan Impurity 17
- Tolvaptan impurity 2
- Tolvaptan Impurity 20