4-*difluoro(3,4,5-trifluorophenoxy)-methyl]-3,5-difluoro-4'-propyl-1,1'-biphenyl Chemical Properties

Melting point:

42.511℃ (acetic acid )

Boiling point:

431.6±45.0 °C(Predicted)

Density 

1.332±0.06 g/cm3(Predicted)

vapor pressure 

0.013-0.29Pa at 20-50℃

storage temp. 

Sealed in dry,Room Temperature

solubility 

soluble in Methanol

form 

Crystalline

color 

White to Almost white

LogP

6.5 at 25℃ and pH6.1

CAS DataBase Reference

303186-20-1

Safety Information

HS Code 

2909.30.6000

4-*difluoro(3,4,5-trifluorophenoxy)-methyl]-3,5-difluoro-4'-propyl-1,1'-biphenyl Usage And Synthesis

Chemical Properties

White Crystalline

Uses

4-*difluoro(3,4,5-trifluorophenoxy)-methyl]-3,5-difluoro-4'-propyl-1,1'-biphenyl is a liquid crystal with a difluoromethyleneoxy linkage group for active-matrix displays

Preparation

The preparation of 4-*difluoro(3,4,5-trifluorophenoxy)-methyl]-3,5-difluoro-4'-propyl-1,1'-biphenyl is as follows:In a fluororesin container 3,5-Difluoro-4'-propylbiphenyl-4-thionocarboxylic acid 3,4,5-trifluorophenyl ester (1.65 g, 3.9 mmol), ethyl acetate (10 mL) was added, Further, iodine pentafluoride (IF 5) (0.86 g, 3.9 mmol),And triethylamine · trihydrofluoride salt (NEt3 - 3HF)(0.62 g, 3.9 mmol), and the mixture was stirred at 65 ° C. for 6 hours. After stopping the reaction with an alkali, the organic layer was distilled off under reduced pressure, and the residue was purified by silica gel column chromatography and recrystallization to obtainTo obtain 4- [difluoro- (3,4,5-trifluorophenoxy) -methyl] -3,5-difluoro-4'-propylbiphenyl (1.50 g, 3.5 mmol). The isolation yield was 90%, and the purity was 99.88%.

4-*difluoro(3,4,5-trifluorophenoxy)-methyl]-3,5-difluoro-4'-propyl-1,1'-biphenyl(303186-20-1)Related Product Information

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