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2'-O-(2-Methoxyethyl)guanosine

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2'-O-(2-Methoxyethyl)guanosine Basic information

Product Name:
2'-O-(2-Methoxyethyl)guanosine
Synonyms:
  • Guanosine, 2'-O-(2-Methoxyethyl)-
  • 2'-O-(2-Methoxyethyl)guanosine
  • 2-amino-9-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)-1,9-dihydro-6H-purin-6-one
  • 2'-MOE-rG
  • 2'-O-(2-Methoxyethyl)-guanosine, >97%
  • 2'-O-MOE-Gr
  • 2'-O-Methoxyethyl-guanosine
  • 2'-O-MOE-rG
CAS:
473278-54-5
MF:
C13H19N5O6
MW:
341.32
EINECS:
1308068-626-2
Product Categories:
  • Bases & Related Reagents
  • Carbohydrates & Derivatives
  • Heterocycles
  • Nucleotides
  • Modified(deoxy)nucleoside
  • Nucleosides-2'-O-MOE Nucleosides
Mol File:
473278-54-5.mol
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2'-O-(2-Methoxyethyl)guanosine Chemical Properties

Boiling point:
715.0±70.0 °C(Predicted)
Density 
1.81±0.1 g/cm3(Predicted)
storage temp. 
2-8°C(protect from light)
pka
13.20±0.70(Predicted)
form 
Solid
color 
White to off-white
InChI
InChI=1S/C13H19N5O6/c1-22-2-3-23-9-8(20)6(4-19)24-12(9)18-5-15-7-10(18)16-13(14)17-11(7)21/h5-6,8-9,12,19-20H,2-4H2,1H3,(H3,14,16,17,21)/t6-,8-,9-,12-/m1/s1
InChIKey
DLLBJSLIKOKFHE-WOUKDFQISA-N
SMILES
OC[C@H]1O[C@@H](N2C3=C(C(NC(=N3)N)=O)N=C2)[C@H](OCCOC)[C@@H]1O
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2'-O-(2-Methoxyethyl)guanosine Usage And Synthesis

Description

2'-O-(2-Methoxyethyl)-guanosine is a guanosine derivative isolated from the reaction of 2-aminoadenosine with methylsulfonyl chloride. 2'-O-(2-Methoxyethyl)-guanosine can be used as a building block for cross-linking oligonucleotides.

Uses

A guanosine derivative as building blocks for cross-linking oligonucleotides.

Definition

2'-O-(2-Methoxyethyl)guanosine, a 2′-O-methoxyethyl-modified nucleoside, can be produced by enzymatic conversion (adenosine deaminase) from 2′-O-(2-methoxyethyl)-2,6-diaminopurine riboside.

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