(R)-(+)-Tolvaptan Chemical Properties

Melting point:

>167°C (dec.)

storage temp. 

Refrigerator

solubility 

Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)

form 

Solid

color 

Off-White

(R)-(+)-Tolvaptan Usage And Synthesis

Uses

An enantiomer of Tolvaptan. It is a selective, competitive arginine vasopressin V2 receptor antagonist used to treat hyponatremia (low blood sodium levels) associated with congestive heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone (SIADH).

(R)-(+)-Tolvaptan(331947-66-1)Related Product Information

• 5-Dehydro Tolvaptan
• (S)-(-)-Tolvaptan
• Benzamide, N-[4-[[(4S,5S)-7-chloro-2,3,4,5-tetrahydro-4,5-dihydroxy-1H-1-benzazepin-1-yl]carbonyl]-3-methylphenyl]-2-methyl-
• Benzoic acid, 2-methyl-4-[(2-methylbenzoyl)[2-methyl-4-[(2-methylbenzoyl)amino]benzoyl]amino]-
• Rac-Trans-4-Hydroxy Tolvaptan
• 5-Chloro-2-[[(4-methylphenyl)sulfonyl]amino]benzoic acid methyl ester
• Benzamide, N-[4-[(7-chloro-2,3,4,5-tetrahydro-5-oxo-1H-1-benzazepin-1-yl)carbonyl]-3-methylphenyl]-2-methyl-4-[(2-methylbenzoyl)amino]-
• N-(4-(7-chloro-5-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)phenyl)-2-methylbenzamide
• Tolvaptan Impurity 3 (DM-4104)
• Tolvaptan Impurity 65
• AJMZAIPORREFDJ-UHFFFAOYSA-N
• Tolvaptan Impurity 11
• N-[4-[[7-Chloro-2,3,4,5-tetrahydro-5-(phosphonooxy)-1H-1-benzazepin-1-yl]carbonyl]-3-methylphenyl]-2-methylbenzamide
• Tolvaptan Impurity 4 (DM-4105)
• Tolvaptan Impurity 7
• 3-Chloro-2-methylbenzoyl chloride
• Tolvaptan Impurity 25
• N-[4-[(7-Chloro-2,3,4,5-tetrahydro-5-oxo-1H-1-benzazepin-1-yl)carbonyl]-3-methylphenyl]-2-methyl-N-(2-methylbenzoyl)-4-[(2-methylbenzoyl)amino]benzamide