Neostenine
Neostenine Basic information
- Product Name:
- Neostenine
- Synonyms:
-
- Neostenine
- Furo[2,3-h]pyrrolo[3,2,1-jk][1]benzazepin-10(2H)-one, 8-ethyldodecahydro-11-methyl-, (7aR,8R,8aR,11S,11aR,11bS,11cR)-
- CAS:
- 477953-07-4
- MF:
- C17H27NO2
- MW:
- 277.4
- Mol File:
- 477953-07-4.mol
More
Less
Neostenine Chemical Properties
- Boiling point:
- 414.6±45.0 °C(Predicted)
- Density
- 1.12±0.1 g/cm3(Predicted)
- pka
- 9.93±0.60(Predicted)
More
Less
Neostenine Usage And Synthesis
Uses
Neostenine is a stenine-type Stemona alkaloid, with antitussive activity. Neostenine is also a substrate of P-glycoprotein with high absorptive permeability in Caco-2 monolayer model. Neostenine also shows oral activity for intestinal application[1][2].
References
[1] Chung HS, et al. Antitussive activity of Stemona alkaloids from Stemona tuberosa. Planta Med. 2003 Oct;69(10):914-20. DOI:10.1055/s-2003-45100
[2] Leung PH, et al. Intestinal absorption of Stemona alkaloids in a Caco-2 cell model. Planta Med. 2006 Feb;72(3):211-6. DOI:10.1055/s-2005-916195
NeostenineSupplier
Chembest Research Laboratories Limited
- Tel
- +86-21-20908456
- sales@BioChemBest.com
BioBioPha Co., Ltd.
- Tel
- 0871-65217109 13211707573;
- y.liu@mail.biobiopha.com
Sichuan Wei Keqi Biological Technology Co., Ltd.
- Tel
- 028-81700200 18116577057
- 3003855609@qq.com
Wuxi Zhongkun Biochemical Technology Co., Ltd.
- Tel
- 0510-85629785 18013409632
- sales@reading-chemicals.com
Shanghai Yongye Biotechnology Co., Ltd.
- Tel
- 86-021-61559134 15921386130
- 3423497944@qq.com