oxetan-3-yl-acetic acid ethyl ester Chemical Properties

storage temp. 

2-8°C

Appearance

Colorless to light yellow Liquid

Safety Information

HS Code 

2932990090

oxetan-3-yl-acetic acid ethyl ester Usage And Synthesis

Uses

With the structure oxetane, oxetan-3-yl-acetic acid ethyl ester can be used as drug intermediate. In medicinal chemistry, oxetanes have received enormous interest as replacement groups for gem-dimethyl and carbonyl groups with improved physicochemical properties. The small, polar nature of the heterocycle has led to its incorporation as a pendant motif to improve druglike properties.[1]

References

[1] Oxetanes: Recent Advances in Synthesis, Reactivity, and Medicinal Chemistry. Rev. 2016, 116, 19, 12150–12233. DOI:10.1021/acs.chemrev.6b00274

oxetan-3-yl-acetic acid ethyl ester(1207175-04-9)Related Product Information

• ethyl 2-(oxetan-3-ylidene)acetate
• oxetane-2-carboxylic acid methyl ester
• oxetane-2-carboxylic acid ethyl ester
• 1,1,1-trifluoro-3-oxetanyl Methanesulfonic acid ester
• oxetan-3-ylmethanol
• 3,3-Oxetanedimethanamine
• Oxetan-3-aMine oxalate
• oxetane-3-carbaldehyde
• C-Oxetan-3-yl-methylamine hydrochloride
• OXETAN-3-AMINE HYDROCHLORIDE
• 3-Oxetanone
• 3,3-bisz-(Hydroxymethyl)-oxetane
• Benzyl oxetan-3-ylcarbamate
• 3-Oxetanecarbonitrile
• 3-Oxetanemethanol
• Oxetan-3-ylmethyl 4-methylbenzenesulfonate
• Oxetan-3-ol
• TOLUENE-4-SULFONIC ACID OXETAN-2-YLMETHYL ESTER