1-(PERFLUOROHEXYL)OCTANE Chemical Properties

Melting point:

4.96 °C

Boiling point:

340 °C

Density 

1.331 g/cm3(Temp: 25 °C)

vapor pressure 

3.857Pa at 25℃

storage temp. 

Storage temp. 2-8°C

solubility 

Ethanol: Sparingly soluble: 1-10 mg/mL

form 

liquid

color 

Clear

Water Solubility 

0.992ng/L at 25℃

InChI

InChI=1S/C14H17F13/c1-2-3-4-5-6-7-8-9(15,16)10(17,18)11(19,20)12(21,22)13(23,24)14(25,26)27/h2-8H2,1H3

InChIKey

WRYIIOKOQSICTB-UHFFFAOYSA-N

SMILES

C(F)(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)CCCCCCCC

LogP

10.01 at 25℃

Surface tension

19.65mN/m at 298.15K

EPA Substance Registry System

1-(Perfluorohexyl)octane (133331-77-8)

Safety Information

Hazard Codes 

Xi

HS Code 

2903499090

1-(PERFLUOROHEXYL)OCTANE Usage And Synthesis

Uses

1-(Perfluorohexyl)octane is used in preparation of Fluoroalkane by reduction of Halofluoroalkane in presence of precious metal catalyst and inorganic compound.

Definition

ChEBI: Perfluorohexyloctane is a fluoroalkane that is tetradecane in which all of the hydrogen atoms at positions 1, 2, 3, 4, 5, and 6 have been replaced by fluorine atoms. It is an ophthalmic solution used to treat the signs and symptoms of dry eye disease. It has a role as an ophthalmology drug and a nonionic surfactant. It is a fluorohydrocarbon and a fluoroalkane. It derives from a hydride of a tetradecane.

Flammability and Explosibility

Non flammable

References

[1] PRIYANKA AGARWAL . Semifluorinated alkane based systems for enhanced corneal penetration of poorly soluble drugs[J]. International Journal of Pharmaceutics, 2018, 538 1: Pages 119-129. DOI: 10.1016/j.ijpharm.2018.01.019
[2] PRIYANKA AGARWAL . Preclinical studies evaluating the effect of semifluorinated alkanes on ocular surface and tear fluid dynamics[J]. Ocular Surface, 2019, 17 2: Pages 241-249. DOI: 10.1016/j.jtos.2019.02.010

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