FMoc-NH-PEG9-CH2CH2COOH Chemical Properties

Boiling point:

803.9±65.0 °C(Predicted)

Density 

1.186±0.06 g/cm3 (20 ºC 760 Torr)

storage temp. 

2-8°C

solubility 

Soluble in DMSO, DCM, DMF

pka

4.28±0.10(Predicted)

Safety Information

HS Code 

2924297099

FMoc-NH-PEG9-CH2CH2COOH Usage And Synthesis

Description

Fmoc-N-amido-PEG9-acid is a PEG linker containing an Fmoc-protected amine and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Uses

Fmoc-N-amido-PEG9 Acid is used as a reactant in the synthesis of novel PEG-linked dimeric modulators for CXCR4.

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