alpha, oMega-DisucciniMidyl hexaethylene glycol CAS#: 1334170-02-3

alpha, oMega-DisucciniMidyl hexaethylene glycol Basic information

Product Name:

alpha, oMega-DisucciniMidyl hexaethylene glycol

Synonyms:

alpha, oMega-DisucciniMidyl hexaethylene glycol
NHS-PEG6-NHS
Bis-PEG7-NHS ester
α,ω-disuccinimidyl hexaethylene glycol
4,7,10,13,16,19,22-Heptaoxapentacosanedioic acid, 1,25-bis(2,5-dioxo-1-pyrrolidinyl) ester
Bis-dPEG7-NHS ester
Di-NHS Ester-PEG7
(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[2-[2-[3-(2,5-dioxopyrrolidin-1-yl)oxy-3-oxo-propoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate

CAS:

1334170-02-3

MF:

C26H40N2O15

MW:

620.6

Product Categories:

Homobifunctional PEG

Mol File:

1334170-02-3.mol

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alpha, oMega-DisucciniMidyl hexaethylene glycol Chemical Properties

solubility: Soluble in DMSO, DCM, DMF

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alpha, oMega-DisucciniMidyl hexaethylene glycol Usage And Synthesis

Description

Bis-PEG7-NHS ester is a PEG linker containing two NHS ester groups. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.

Biological Activity

Bis-PEG7-NHS ester is a PROTAC bridge, belonging to the PEG class and the Alkyl/ether class. It can be used to synthesize a series of PROTAC molecules. It is a cleavable ADC linker for the synthesis of antibody drug conjugates (ADCs).

target

Cleavable

PEGs

Alkyl/ether

alpha, oMega-DisucciniMidyl hexaethylene glycolSupplier

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