AEEA-AEEA Chemical Properties

Melting point:

133 - 135°C

Boiling point:

548.7±50.0 °C(Predicted)

Density 

1.202±0.06 g/cm3(Predicted)

storage temp. 

-20°C Freezer, Under inert atmosphere

solubility 

DMSO (Slightly, Heated, Sonicated), Methanol (Slightly)

pka

3.39±0.10(Predicted)

form 

Solid

color 

White to Off-White

InChI

InChI=1S/C12H24N2O7/c13-1-3-18-5-7-20-9-11(15)14-2-4-19-6-8-21-10-12(16)17/h1-10,13H2,(H,14,15)(H,16,17)

InChIKey

YQZVQKYXWPIKIX-UHFFFAOYSA-N

SMILES

C(O)(=O)COCCOCCNC(=O)COCCOCCN

CAS DataBase Reference

1143516-05-5

Safety Information

HS Code 

2924190090

AEEA-AEEA Usage And Synthesis

Description

17-Amino-10-oxo-3,6,12,15-tetraoxa-9-azaheptadecanoic Acid (AEEA-AEEA) is a Semaglutide intermediate used in the preparation of glutamate-containing acylation reagents, as well as in the selective acylation of amino groups in peptides or proteins.

Chemical Properties

White crystalline powder

Uses

17-Amino-10-oxo-3,6,12,15-tetraoxa-9-azaheptadecanoic Acid is used for preparation of glutamic acid-containing acylating reagents for selective acylation of amino group(s) in peptides or proteins.

Synthesis

17-Amino-10-oxo-3,6,12,15-tetraoxa-9-azaheptadecanoic Acid is synthesized by Hydrolysis Reaction of 12,12-Dimethyl-10-oxo-3,6,11-trioxa-9-azatridecanoic acid  with Hydrolysis Reaction in Dichloromethane for 2h.

AEEA-AEEA(1143516-05-5)Related Product Information

• H2N-PEG8-OH
• H2N-PEG12-OH
• Amino-PEG6-alcohol
• 1-AMINO-3,6,9-TRIOXAUNDECANYL-11-OL
• 2-[2-(2-AMINOETHOXY)ETHOXY]ETHANOL
• Fmoc-L-Lys[Oct-(otBu)-Glu-(otBu)-AEEA-AEEA]-OH
• Fmoc-8-amino-3,6-dioxaoctanoic acid
• BOC-8-AMINO-3,6-DIOXAOCTANOIC ACID DCHA
• Boc-His(Trt)-Aib-OH
• 17-Amino-10-oxo-3,6,12,15-tetraoxa-9-azaheptadecanoic Acid