GAMMA-GLU-CYS TRIFLUOROACETATE SALT Chemical Properties

Melting point:

167℃

Boiling point:

592.4±50.0 °C(Predicted)

Density 

1.436±0.06 g/cm3(Predicted)

storage temp. 

-20°C

solubility 

≥ 25mg/mL in Water, ≥ 52 mg/mL in DMSO, ≥ 54.8 mg/mL in EtOH

pka

2.21±0.10(Predicted)

InChIKey

RITKHVBHSGLULN-WHFBIAKZSA-N

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

GAMMA-GLU-CYS TRIFLUOROACETATE SALT Usage And Synthesis

Description

Gamma-glutamylcysteine (γ-Glutamylcysteine) is a cysteine and glutamic acid-containing dipeptide that is a precursor to glutathione (GSH). Gamma-glutamylcysteine is a cofactor for glutathione peroxidase (GPx) to increase GSH levels.

Uses

γ-Glu-Cys is used to study the active sites and kinetics of glutathione synthetase(s). It has also been used for the extraction and quantification of low molecular weight thiols from Arabidopsis tissues.

Definition

ChEBI: A molecular entity formed when L-cysteine amino group binds to the gamma-carbonyl of L-glutamic acid.

Biochem/physiol Actions

γ-L-Glutamyl-L-cysteine (γ-Glu-Cys) is a substrate used for the biosynthesis of L-glutathione by glutathione synthetase(s). γ-Glu-Cys is generated by the cleavage of the Cys-Gly peptide bond of glutathione. It is also essential for the formation of phytochelatins, which are cysteine-rich thiol-reactive peptides.

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