(S)-Tenofovir Chemical Properties

Melting point:

>260°C (dec.)

Boiling point:

616.1±65.0 °C(Predicted)

Density 

1.79±0.1 g/cm3(Predicted)

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

solubility 

DMSO (Slightly), Methanol (Slightly), Water (Slightly)

pka

2.36±0.10(Predicted)

form 

Solid

color 

White to Off-White

optical activity

Consistent with structure

InChI

InChI=1S/C9H14N5O4P/c1-6(18-5-19(15,16)17)2-14-4-13-7-8(10)11-3-12-9(7)14/h3-4,6H,2,5H2,1H3,(H2,10,11,12)(H2,15,16,17)/t6-/m0/s1

InChIKey

SGOIRFVFHAKUTI-LURJTMIESA-N

SMILES

P(CO[C@@H](C)CN1C2C(N=C1)=C(N)N=CN=2)(=O)(O)O

(S)-Tenofovir Usage And Synthesis

Uses

(S)-Tenofovir is an S-enatiomeric derivative of Tenofovir (T018500). (S)-Tenofovir displays virucidal activity against herpes, visna virus and retrovirus. The S enantiomer of Tenofovir (T018500) is less effective against HIV than their (R)-enantiomeric counterparts.

(S)-Tenofovir(147127-19-3)Related Product Information

• Diethyl-carbaMic Acid ChloroMethyl Ester
• Mono-POC Isopropyl Tenofovir (Mixture of DiastereoMers)
• Tenofovir Impurity 95
• (R)-(((1-(6-amino-3H-purin-3-yl)propan-2-yl)oxy)methyl)phosphonic acid
• Tenofovir Disopropyl Ethyl Diester
• Tenofovir
• Chloromethyl isopropyl carbonate
• rac-Tenofovir-d7
• 6N-HydroxyMethyl Tenofovir Disoproxil
• D-Alanine Isopropyl Ester HCl
• Diethyl (tosyloxy)methylphosphonate
• 2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[(1R)-2-[6-[[[[9-[(2R)-5-hydroxy-2,11-diMethyl-5-oxido-9-oxo-3,6,8,10-tetraoxa-5-phosphadodec-1-yl]-9H-purin-6-yl]aMino]Methyl]aMino]-9H-purin-9-yl]-1-Methylethoxy]Methyl]-, 1,9-bis(1-Methylethyl) ester, 5-ox
• (S)-(((1-(6-aMino-9H-purin-9-yl)propan-2-yloxy)Methyl)phosphoryl)bis(oxy)bis(Methylene) isopropyl dicarbonate fuMarate
• Tenofovir disoproxil fumarate
• Diisopropyl carbonate
• ChloroMethyl Propyl Carbonate
• Tenofovir Disoproxil Related Compound B (10 mg) ((E)-9-(Prop-1-enyl)-9H-purin-6-amine)
• Allene