Ferric pyrophosphate Chemical Properties

storage temp. 

Store at RT.

solubility 

Water

form 

soluble crystals

color 

Yellow powder

Odor

Odorless

Water Solubility 

insoluble H2O, acetic acid; soluble mineral acids [MER06]

Stability:

Hygroscopic

InChIKey

CADNYOZXMIKYPR-UHFFFAOYSA-B

LogP

-3.420 (est)

CAS DataBase Reference

10058-44-3(CAS DataBase Reference)

EPA Substance Registry System

Diphosphoric acid, iron(3+) salt (3:4) (10058-44-3)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

HS Code 

2835390000

Hazardous Substances Data

10058-44-3(Hazardous Substances Data)

MSDS

• Language:English Provider:Diphosphoric acid iron(III) salt

Ferric pyrophosphate Usage And Synthesis

Description

Iron, which is the chief constituent of Earth’s core, is the most abundant element in Earth as a whole (about 35 percent) . Ferric pyrophosphate is an iron replacement product, is a mixed-ligand iron complex in which iron (III) is bound to pyrophosphate and citrate. It is widely used to fortify cereal flours and infant cereals, dispersible ferric pyrophosphate is as well absorbed as ferrous sulfate in adults. pyrophosphate ions participate in the ion transfer processes. These ions, as chelating agents, would release iron from transferrin and form a ferric pyrophosphate complex, and that pyrophosphate alone has the ability to mediate iron exchange from transferring to ferritin. Ferric pyrophosphate citrate should only be added to the bicarbonate concentrate; do not add to acid concentrate mixtures. Ferric pyrophosphate citrate is not intended for use in patients receiving peritoneal dialysis; it has not been studied in patients receiving home hemodialysis.

Chemical Properties

Ferric pyrophosphate (iron(III)pyrophosphate, Fe4(P207)3*xH2O) is a tan or yellowish-white odorless powder or Soluble crystals. It is insoluble in water but is soluble in mineral acids. It is prepared by reacting sodium pyrophosphate with ferric citrate.

Ferric pyrophosphate is an important kind of compounds insoluble in water and also poorly soluble in dilute acid. It does not modify organoleptic characteristics of foods because of its white colour and low reactivity, making it suitable for many difficult-to-fortify food vehicles, such as salt, cereals, infant formulas, and rice. It has been demonstrated to be an effective iron fortificant from efficacy studies. However, the poor solubility of ferric pyrophosphate in gastric juice limits its bioavailability, which furthemore reduces its nutritional value. The relative bioavailability value (RBV) of ferric pyrophosphate was reported to be only about 50% from human studies.

Uses

Iron(III) Pyrophosphate can be used as an iron supplement for people with iron deficiencies.

Uses

Food and Feed additives/Food additives

Uses

Ferric Pyrophosphate is a nutrient supplement, tan or yellowish white in color, prepared by reacting sodium pyrophosphate with ferric citrate. the ingredient may be used in infant formula. it is also termed iron (iii) pyrophosphate.

Preparation

Ferric pyrophosphate was prepared by adding sodium pyrophosphate solution to ferric chloride solution.
2Fe2(SO4)3+3Na4P2O7=Fe4(P2O7)3+6Na2SO4
The precipitate collected was washed and a ferric pyrophosphate suspension was dispersed with lecithin and other emulsifiers.

Definition

ChEBI: Ferric pyrophosphate is an iron coordination entity composed from Fe(3+) cations and diphosphate(4-) anions in a 4:3 ratio. It contains a diphosphate(4-).

General Description

Ferric Phosphate is a tan or yellowish white odorless powder. It is insoluble in water and soluble in mineral acids. It can be prepared by reacting sodium pyrophosphate with ferric citrate. It shows good bioaccesibility.

Flammability and Explosibility

Non flammable

Safety Profile

When heated to decomposition it emits very toxic fumes of POx.

Ferric pyrophosphate(10058-44-3)Related Product Information

• Ammonium ferric citrate
• Ferric chloride
• 5-Chlorovaleric acid
• Pyrophosphoric acid
• Diphenolic acid
• Tetrasodium pyrophosphate
• 4-(Diethylamino)salicylaldehyde
• IRON(III) PHOSPHATE DIHYDRATE
• Folic acid
• Citric acid
• Ferric phosphate
• Ethyl 2-(Chlorosulfonyl)acetate
• Pralmorelin
• Hematite
• DL-α-Tocopherol
• Hyaluronic acid
• Stannous pyrophosphate
• Copper Pyrophosphate