ChemicalBook > Product Catalog > Biochemical Engineering > Inhibitors > PI3K / Akt / mTOR > Akt inhibitors > AKT Kinase Inhibitor
AKT Kinase Inhibitor
AKT Kinase Inhibitor Basic information
- Product Name:
- AKT Kinase Inhibitor
- Synonyms:
-
- AKT Kinase Inhibitor
- 3-[2-(4-Amino-1,2,5-oxadiazol-3-yl)-7-(3-aminopropoxy)-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl]-2-propyn-1-ol
- 2-Propyn-1-ol, 3-[2-(4-aMino-1,2,5-oxadiazol-3-yl)-7-(3-aMinopropoxy)-1-ethyl-1H-iMidazo[4,5-c]pyridin-4-yl]-
- AKT Kinase Inhibitor (2-Propyn-1-ol, 3-[2-(4-amino-1,2,5-oxadiazol-3-yl)-7-(3-aminopropoxy)-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl]-)
- 3-[2-(4-amino-1
- 5-c]pyridin-4-yl]-
- 5-oxadiazol-3-yl)-7-(3-aminopropoxy)-1-ethyl-1H-imidazo[4
- AKT Kinase Inhibitor USP/EP/BP
- CAS:
- 842148-40-7
- MF:
- C16H19N7O3
- MW:
- 357.37
- Mol File:
- 842148-40-7.mol
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AKT Kinase Inhibitor Chemical Properties
- Boiling point:
- 678.8±65.0 °C(Predicted)
- Density
- 1.50
- storage temp.
- Store at -20°C
- solubility
- DMSO : 16.67 mg/mL (46.65 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
- form
- Powder
- pka
- 12.98±0.10(Predicted)
- color
- White to light yellow
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AKT Kinase Inhibitor Usage And Synthesis
Biological Activity
AKT Kinase Inhibitor is an Akt inhibitor with antitumor activity.
in vivo
Trop-2 expressing tumors subcutaneously injected in animal models show a striking reduction of growth following treatment with specific drugs that inhibit Akt activity. Therefore Akt has a central functional role in mediating the Trop-2-dependent growth stimulus.
target
| Akt
|
AKT Kinase InhibitorSupplier
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