6-broMo-8-cyclopentyl-5-Methyl-2-(5-(piperazin-1-yl)pyridin-2-ylaMino)pyrido[2,3-d]pyriMidin-7(8H)-one
6-broMo-8-cyclopentyl-5-Methyl-2-(5-(piperazin-1-yl)pyridin-2-ylaMino)pyrido[2,3-d]pyriMidin-7(8H)-one Basic information
- Product Name:
- 6-broMo-8-cyclopentyl-5-Methyl-2-(5-(piperazin-1-yl)pyridin-2-ylaMino)pyrido[2,3-d]pyriMidin-7(8H)-one
- Synonyms:
-
- 6-broMo-8-cyclopentyl-5-Methyl-2-(5-(piperazin-1-yl)pyridin-2-ylaMino)pyrido[2,3-d]pyriMidin-7(8H)-one
- 6-Bromo-8-cyclopentyl-5-methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]-pyrido[2,3-d]pyrimidin-7(8H)-one
- 4-(6-((6-bromo-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carboxylate
- 6-Bromo-8-cyclopentyl-5-methyl-2-(5-piperazin-1-yl-pyridin-2-ylamino)-8H-pyrido[2,3-d]pyrimidin-7-one
- Palbociclib-013
- 6-broMo-8-cyclopentyl-5-Methyl-2-(5-(piperazin-1-yl)pyridin-2-ylaMino)pyrido[2,3-d]pyriMidin-7(8H)-one6-broMo-8-cyclopentyl-5-Methyl-2-(5-(piperazin-1-yl)pyridin-2-ylaMino)pyrido[2,3-d]pyriMidin-7(8H)-one
- Palbociclib impurity 16/6-broMo-8-cyclopentyl-5-Methyl-2-(5-(piperazin-1-yl)pyridin- 2-ylaMino)pyrido[2,3-d]pyriMidin-7(8H)-one
- Pyrido[2,3-d]pyrimidin-7(8H)-one, 6-bromo-8-cyclopentyl-5-methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]-
- CAS:
- 851067-56-6
- MF:
- C22H26BrN7O
- MW:
- 484.39
- Mol File:
- 851067-56-6.mol
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6-broMo-8-cyclopentyl-5-Methyl-2-(5-(piperazin-1-yl)pyridin-2-ylaMino)pyrido[2,3-d]pyriMidin-7(8H)-one Chemical Properties
- Boiling point:
- 682.2±65.0 °C(Predicted)
- Density
- 1.495±0.06 g/cm3(Predicted)
- solubility
- Aqueous Acid (Slightly), DMSO (Slightly, Heated), DMF (Slightly, Heated)
- pka
- 8.66±0.10(Predicted)
- form
- Solid
- color
- Off-White to Yellow
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6-broMo-8-cyclopentyl-5-Methyl-2-(5-(piperazin-1-yl)pyridin-2-ylaMino)pyrido[2,3-d]pyriMidin-7(8H)-one Usage And Synthesis
Uses
6-Desacetyl-6-Bromo Palbociclib is an impurity of Palbociclib (P139900),(also known as compound number PD-0332991) is an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.Also, it is derived from 6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido-[2,3-d]pyrimidin-7(8H)-one (B682195), which is used to prepare pyridino[2,3-d]pyrimidin-7(8H)-one derivatives as CDK4 and/or CDK6 inhibitors useful in the treatment of diseases.
6-broMo-8-cyclopentyl-5-Methyl-2-(5-(piperazin-1-yl)pyridin-2-ylaMino)pyrido[2,3-d]pyriMidin-7(8H)-oneSupplier
Arizest(Shanghai)Pharmatech Co.,Ltd Gold
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- 60753300-53010 13671599112
- geshi.zhuang@acebright.com
Daicel Chiral Technologies (China)CO.,LTD
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- 021-50460086-9 15921403865
- han_yajun@dctc.daicel.com
Beijing Comparison Pharmaceutical Technology Co., Ltd
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- 010-010-52878169 15801002657
- sales@bjcomparison.com
SHANGHAI FORTUNE CHEMICAL TECHNOLOGY CO., LTD
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- 13816107857
- sales@fortunechem-sh.com
ChemStrong Scientific Co.,Ltd
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- 0755-0755-66853366 13670046396
- sales@chem-strong.com
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6-broMo-8-cyclopentyl-5-Methyl-2-(5-(piperazin-1-yl)pyridin-2-ylaMino)pyrido[2,3-d]pyriMidin-7(8H)-one(851067-56-6)Related Product Information
- Everolimus
- PLERIXAFOR
- Parecoxib
- Palbociclib Impurity 7
- 2-chloro-4-(cyclopentylamino)-5-pyrimidinyl ethanone
- Palbociclib
- Palbociclib Impurity 8
- Exemestane
- PalBociclib Impurity 22
- Pyrido[2,3-d]pyriMidin-7(8H)-one, 8-cyclopentyl-5-Methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]aMino]-
- Phosphine oxide, tris (2-methylphenyl)-
- Palbociclib-030
- tert-butyl 4-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carboxylate
- 1-Piperazinecarboxylic acid, 4-(2-aMino-3-pyridinyl)-, 1,1-diMethylethyl ester
- 5-(piperazin-1-yl)pyridin-2-aMine
- Palbociclib-012
- 6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one
- PD 0332991 HCl