ChemicalBook > Product Catalog > Analytical Chemistry > Standard > Standard Substance > 6-HYDROXYCHLORZOXAZONE
6-HYDROXYCHLORZOXAZONE
6-HYDROXYCHLORZOXAZONE Basic information
- Product Name:
- 6-HYDROXYCHLORZOXAZONE
- Synonyms:
-
- 5-chloro-6-hydroxy-2-benzoxazolinon
- 5-chloro-6-hydroxy-2-benzoxazolinone
- CHLORZOXAZONE, 6-HYDROXY MAJOR METABOLIT E OF C
- 6-Hydroxychlorzoxazone solution
- 6-Hydroxy Chlorzoxazone-15N-d2
- 5-Chloro-6-hydroxy-2(3H)-benzoxazolone, 5-Chloro-6-hydroxybenzoxazone
- 5-Chloro-6-hydroxybenzoxazol-2(3H)-one
- 5-chloro-6-hydroxy-3H-1,3-benzoxazol-2-one
- CAS:
- 1750-45-4
- MF:
- C7H4ClNO3
- MW:
- 185.56
- EINECS:
- 621-147-2
- Product Categories:
-
- Various Metabolites and Impurities
- Intermediates & Fine Chemicals
- Metabolites & Impurities
- Pharmaceuticals
- Mol File:
- 1750-45-4.mol
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6-HYDROXYCHLORZOXAZONE Chemical Properties
- Melting point:
- 240-242°C
- Density
- 1.649±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- methanol: soluble
- form
- Solid
- pka
- 7.83±0.70(Predicted)
- color
- white to pink
- CAS DataBase Reference
- 1750-45-4
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Safety Information
- Hazard Codes
- Xi,T,F
- Risk Statements
- 36/37/38-39/23/24/25-23/24/25-11
- Safety Statements
- 26-45-36/37-16-7
- WGK Germany
- 2
- RTECS
- DM5260000
- HS Code
- 29349990
MSDS
- Language:English Provider:SigmaAldrich
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6-HYDROXYCHLORZOXAZONE Usage And Synthesis
Chemical Properties
Off-White Solid
Uses
6-Hydroxychlorzoxazone has been used for HPLC-based metabolic assays of chlorzoxazone.
Uses
A major metabolite of chlorzoxazone. Formed by the actions of cytochrome P450IIE1
Definition
ChEBI: 6-Hydroxychlorzoxazone is a benzoxazole.
Biochem/physiol Actions
6-hydroxy Chlorzoxazone is a novel metabolite of chlorzoxazone. It is formed by the hydroxylation of chlorzoxazone by cytochrome P450 family 2 subfamily E member 1 (CYP2E1) enzyme. The determination of formation and clearance of 6-hydroxychlorzoxazone is used as a reliable marker of CYP2E1 metabolic activity.
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