N-Methyl-N-((3S,4S)-4-Methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyriMidin-4-aMine Chemical Properties

Melting point:

156-160°C

Density 

1?+-.0.06 g/cm3(Predicted)

storage temp. 

2-8°C

solubility 

Methanol (Slightly), Water (Slightly)

pka

13.36±0.50(Predicted)

form 

Solid

color 

Off-White

Stability:

Hygroscopic

N-Methyl-N-((3S,4S)-4-Methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyriMidin-4-aMine Usage And Synthesis

Uses

Tofacitinib impurity N is an impurity of Tofacitinib (T528000), an enantiopure stereoisomer of the drug, Janus kinase 3(Jak3) inhibitor (CP-690,550) that has been found to inhibit selected members of the STE7 and STE20 subfamily of kinases.

N-Methyl-N-((3S,4S)-4-Methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyriMidin-4-aMine(1260614-73-0)Related Product Information

• Tofacitinib
• (3S,4S)-1-benzyl-N,4-diMethylpiperidin-3-aMine
• Tofacitinib related coMpound 2
• 3-((3S,4R)-4-Methyl-3-(Methyl(7H-pyrrolo[2,3-d]pyriMidin-4-yl)aMino)piperidin-1-yl)-3-oxopropanenitrile
• (3R,4R)-N,1,4-trimethyl-N-{7H-pyrrolo[2,3-d]pyrimidin-4-yl}piperidin-3-amine
• Tofacitinib Impurity 19
• 3-((3S,4S)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile
• 3-((3R,4R)-4-Methyl-3-(Methyl(7H-pyrrolo[2,3-d]pyriMidin-4-yl)aMino)piperidin-1-yl)-3-oxopropanaMide
• 6,7-Dihydro-N-methyl-N-[(3R,4R)-4-methyl-3-piperidinyl]-5H-pyrrolo[2,3-d]pyrimidin-4-amine
• R-afatinib
• Tofacitinib Impurity 20
• (S)-N4-(3-chloro-4-fluorophenyl)-7-(tetrahydrofuran-3-yloxy)quinazoline-4,6-diaMine
• (3R,4R)-3-[(6-amino-4-pyrimidinyl)methylamino]-4-methyl-β-oxo-1-Piperidinepropanenitrile
• (3R,4R)-N,4-dimethyl-piperidin-3-amine
• TF-A
• 2-amino-4-fluoro-5-nitrobenzoic acid
• Ethyl S-4-chloro-3-hydroxybutyrate
• Tofacitinib Impurity T