3-Hydroxybakuchiol
3-Hydroxybakuchiol Basic information
- Product Name:
- 3-Hydroxybakuchiol
- Synonyms:
-
- 3-Hydroxybakuchiol
- 4-[(1E,3S)-3-Ethenyl-3,7-dimethyl-1,6-octadien-1-yl]-1,2-benzenediol
- 4-[(1E,3S)-3-ethenyl-3,7-dimethylocta-1,6-dienyl] benzene-1,2-diol
- 1,2-Benzenediol, 4-[(1E,3S)-3-ethenyl-3,7-dimethyl-1,6-octadien-1-yl]-
- CAS:
- 178765-54-3
- MF:
- C18H24O2
- MW:
- 272.38
- Mol File:
- 178765-54-3.mol
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3-Hydroxybakuchiol Chemical Properties
- Boiling point:
- 437.6±45.0 °C(Predicted)
- Density
- 1.030±0.06 g/cm3(Predicted)
- pka
- 9.62±0.10(Predicted)
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3-Hydroxybakuchiol Usage And Synthesis
Uses
3-Hydroxybakuchiol can be isolated from Otholobium mexicanum J. W. Grimes. 3-Hydroxybakuchiol is an electron transport chain (ETC) inhibitor. 3-Hydroxybakuchiol has antitumor activity, and induces tumor cell apoptosis. 3-Hydroxybakuchiol also has moderate inhibitory activity against α-glucosidase (IC50: 345 μM)[1][2].
References
[1] Ja?a F, et al. Tumor cell death induced by the inhibition of mitochondrial electron transport: the effect of 3-hydroxybakuchiol. Toxicol Appl Pharmacol. 2013 Oct 15;272(2):356-64. DOI:10.1016/j.taap.2013.06.005
[2] Suárez AI, et al. Main Constituents and Antidiabetic Properties of Otholobium mexicanum. Nat Prod Commun. 2017 Apr;12(4):533-535. PMID:30520590
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