ChemicalBook > Product Catalog > Biochemical Engineering > Inhibitors > Endocrinology & Hormones > GPR agonists > TAK875
TAK875
TAK875 Basic information
- Product Name:
- TAK875
- Synonyms:
-
- [(3S)-6-({2',6'-dimethyl-4'-[3-(methylsulfonyl)propoxy]biphe-nyl-3-yl}meth-oxy)-2,3-dihydro-1-benzofuran-3-yl]acetic acid hemi-hydrate
- TAK875 (3S)-6-[[2',6'-Dimethyl-4'-[3-(methylsulfonyl)propoxy][1,1'-biphenyl]-3-yl]methoxy]-2,3-dihydro-3-benzofuranacetic acid
- TAK-875(0.5H2O)
- CS-1926
- (3S)-6-[[2',6'-Dimethyl-4'-[3-(methylsulfonyl)propoxy][1,1'-biphenyl]-3-yl]methoxy]-2,3-dihydro-3-benzofuranacetic acid hydrate (2:1)
- TAK875 hemihydrate
- TAK-875 hymihydrate
- TAK-875（b）
- CAS:
- 1374598-80-7
- MF:
- C58H66O15S2
- MW:
- 1067.26564
- Product Categories:
-
- API
- Inhibitors
- Mol File:
- 1374598-80-7.mol
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TAK875 Chemical Properties
- storage temp.
- Store at -20°C
- solubility
- DMSO: 100 mg/mL (187.40 mM);Ethanol: Insoluble
- Water Solubility
- Water: Insoluble
- InChI
- InChI=1S/2C29H32O7S.H2O/c2*1-19-12-25(34-10-5-11-37(3,32)33)13-20(2)29(19)22-7-4-6-21(14-22)17-35-24-8-9-26-23(15-28(30)31)18-36-27(26)16-24;/h2*4,6-9,12-14,16,23H,5,10-11,15,17-18H2,1-3H3,(H,30,31);1H2/t2*23-;/m11./s1
- InChIKey
- OJXYMYYDAVXPIK-IWKNALKQSA-N
- SMILES
- S(C([H])([H])[H])(C([H])([H])C([H])([H])C([H])([H])OC1C([H])=C(C([H])([H])[H])C(=C(C([H])([H])[H])C=1[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])OC1C([H])=C([H])C2=C(C=1[H])OC([H])([H])[C@@]2([H])C([H])([H])C(=O)O[H])(=O)=O.S(C([H])([H])[H])(C([H])([H])C([H])([H])C([H])([H])OC1C([H])=C(C([H])([H])[H])C(=C(C([H])([H])[H])C=1[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])OC1C([H])=C([H])C2=C(C=1[H])OC([H])([H])[C@@]2([H])C([H])([H])C(=O)O[H])(=O)=O.O([H])[H]
- CAS DataBase Reference
- 1374598-80-7
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TAK875 Usage And Synthesis
Characteristics
More potent at activating hGPR40 than oleic acid
Biological Activity
TAK-875 is a selective GPR40 agonist with EC50 of 14 nM, 400-fold more potent than oleic acid.
target
| Target | Value |
| GPR40 (CHO cells expressing human GPR40) | < td class="border-bottom: 1px dotted #ccc;padding: 5px;"> 14 nM(EC50)
TAK875Supplier
Wuhan ariel chemical Co., LTD.
- Tel
- 18986259541 18986259541
- sales@3stc.com
The future of Shanghai Industrial Co., Ltd.
- Tel
- 021-61552785
- sales@shshiji.com
Wuhan Kaymke Chemical Co., Ltd.,
- Tel
- 027-87342388 18086026008
- sales@kaymke.com
Shanghai HuanChuan Industry Co.,Ltd.
- Tel
- 021-61478794
- sales@hcshhai.com
Credit Asia Chemical Co., Ltd.
- Tel
- +86 (21) 61124340