Basic information Safety Supplier Related

19-Epi FK-506

Basic information Safety Supplier Related

19-Epi FK-506 Basic information

Product Name:
19-Epi FK-506
Synonyms:
  • QJJXYPPXXYFBGM-VIJOMOBOSA-N
  • Tacrolimus 19-epimer
  • 19-Epi FK-506
  • tacrolimus difference SECRETARY 19 epimers
  • ascomycin epimeric 19 body
  • Ascomycin 19 epimer
  • Tacrolimus Impurity 8(Tacrolimus EP Impurity G)(Tacrolimus 19-Epimer)
  • Tacrolimus Impurity 6
CAS:
144490-63-1
MF:
C44H69NO12
MW:
804.03
Product Categories:
  • Chiral Reagents, Pharmaceuticals, Intermediates & Fine Chemicals
Mol File:
144490-63-1.mol
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19-Epi FK-506 Chemical Properties

Boiling point:
871.7±75.0 °C(Predicted)
Density 
1.19±0.1 g/cm3(Predicted)
pka
9.97±0.70(Predicted)
InChIKey
QJJXYPPXXYFBGM-ZADLGOIHNA-N
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19-Epi FK-506 Usage And Synthesis

Uses

19-Epi FK-506 is an impurity in the synthesis of FK-506 [Tacrolimus] (F370000), an immunosuppressant that blocks T cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-2. Shown to inhibit the activity of FK-506 binding protein, thereby reversing its effects on sarcoplasmic reticulum Ca+2 release.

19-Epi FK-506Supplier

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