N3-PEG8-CH2CH2COOH CAS#: 1214319-92-2

N3-PEG8-CH2CH2COOH Basic information

Product Name:

N3-PEG8-CH2CH2COOH

Synonyms:

N3-PEG8-CH2CH2COOH
Azido-PEG8-propionic acid
N3-PEG8-COOH
Azido-dPEG(R)8-acid
Azido-dPEG??-acid
Azido-PEG8-CH2CH2COOH
N3-PEG8-CH2CH2COOH/Propanoic acid, 3-[(23-azido-3,6,9,12,15,18,21-heptaoxatricos-1-yl)oxy]-
Azido-dPEG8-acid

CAS:

1214319-92-2

MF:

C19H37N3O10

MW:

467.51118

Product Categories:

peg

Mol File:

1214319-92-2.mol

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N3-PEG8-CH2CH2COOH Chemical Properties

storage temp.: -20°C
solubility: Soluble in Water, DMSO, DCM, DMF
form: solid or viscous liquid

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Safety Information

HS Code: 2929900090

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N3-PEG8-CH2CH2COOH Usage And Synthesis

Description

Azido-PEG8-acid is a aqueous soluble PEG linker containing an azide (N3) and a terminal carboxylic acid (CO2H) group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Biological Activity

N3-PEG8-CH2CH2COOH is a non-cleavable ADC linker containing 8-unit PEG that can be used to synthesize antibody drug conjugates (ADCs). It is also a PROTAC linker, belonging to the PEG class, which can be used to synthesize PROTAC molecules.

target

Non-cleavable

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PEGs

N3-PEG8-CH2CH2COOHSupplier

Biomatrik (Jiaxing) Inc.

Tel: 573-573-82623377 18967387295
Email: sales@biomatrik.cn

Chengdu Pukang Biotechnology Co., Ltd

Tel: 028-82550498 19102685862
Email: sales@pu-kang.com

T&W GROUP

Tel: 021-61551611 13296011611
Email: contact@trustwe.com

Hunan HuaTeng Pharmaceutical Co., Ltd.,

Tel: 400-8592883 15367835770
Email: viola@huatengsci.com

Shanghai Boka-chem Tech. Inc.

Tel: 400-026-1533/(021) 6478-0600
Email: sales@bokachem.com

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