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S,S-Efinaconazole

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S,S-Efinaconazole Basic information

Product Name:
S,S-Efinaconazole
Synonyms:
  • (alphaS,betaS)-alpha-(2,4-Difluorophenyl)-beta-methyl-4-methylene-alpha-(1H-1,2,4-triazol-1-ylmethyl)-1-piperidineethanol
  • Efinaconazole Related Impurity 3
  • (2S,3S)-2-(2,4-difluorophenyl)-3-(4-methylenepiperidin-1-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
  • ent-Efinaconazole
  • S,S-Efinaconazole
  • Efinaconazole Enantiomer
  • Efinaconazole Impurity 19
  • Efinaconazole (2s,3s) Isomer
CAS:
164650-45-7
MF:
C18H22F2N4O
MW:
348.39
Mol File:
164650-45-7.mol
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S,S-Efinaconazole Chemical Properties

Boiling point:
512.2±60.0 °C(Predicted)
Density 
1.26±0.1 g/cm3(Predicted)
pka
12.11±0.29(Predicted)
InChI
InChI=1/C18H22F2N4O/c1-13-5-7-23(8-6-13)14(2)18(25,10-24-12-21-11-22-24)16-4-3-15(19)9-17(16)20/h3-4,9,11-12,14,25H,1,5-8,10H2,2H3/t14-,18-/s3
InChIKey
NFEZZTICAUWDHU-GKGMEZMPNA-N
SMILES
N1([C@@H](C)[C@](C2=CC=C(F)C=C2F)(CN2C=NC=N2)O)CCC(=C)CC1 |&1:1,3,r|
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S,S-Efinaconazole Usage And Synthesis

Uses

ent-Efinaconazole is the S,S-enantiomer of Efinaconazole (E435070); a topical antifungal for onychomycosis.

S,S-EfinaconazoleSupplier

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