ChemicalBook > Product Catalog > Analytical Chemistry > Standard > Pharmaceutical Impurity Reference Standards > (2E)-2-Cyano-3-(3-ethoxy-4-hydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide
(2E)-2-Cyano-3-(3-ethoxy-4-hydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide
(2E)-2-Cyano-3-(3-ethoxy-4-hydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide Basic information
- Product Name:
- (2E)-2-Cyano-3-(3-ethoxy-4-hydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide
- Synonyms:
-
- (2E)-2-Cyano-3-(3-ethoxy-4-hydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide
- Entacapone impurity D
- Entacapone Impurity 20(Entacapone EP Impurity D)
- Imp. D (EP):(2E)-2-Cyano-3-(3-ethoxy-4-hydroxy-5-nitrophenyl)-N,N-diethylprop-2-enamide
- Entacapone Impurity 4（Entacapone EP Impurity D）
- (E)-N,N-diethyl-2-cyano-3-(3-ethoxy-4-hydroxy-5-nitrophenyl)acrylamide
- (E)-2-cyano-3-(3-ethoxy-4-hydroxy-5-nitrophenyl)-N,N-diethylprop-2-enamide
- (2E)-2-Cyano-3-(3-ethoxy-4-hydroxy-
- CAS:
- 857629-79-9
- MF:
- C16H19N3O5
- MW:
- 333.34
- Mol File:
- 857629-79-9.mol
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(2E)-2-Cyano-3-(3-ethoxy-4-hydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide Usage And Synthesis
Uses
(2E)-2-Cyano-3-(3-ethoxy-4-hydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide is an impurity of Entacapone (E558500), a peripherally acting inhibitor of catechol-O-methyl transferase (COMT), an enzyme involved in the metabolism of catecholamine neurotransmitters and related drugs. Antiparkinsonian.
Definition
ChEBI: 3-O-ethylentacapone is a C-nitro compound that is entacapone in which the phenolic hydroxy group that is meta to the nitro group has been converted into the corresponding ethyl ether. It is a monocarboxylic acid amide, a nitrile, an aromatic ether and a member of 2-nitrophenols. It is functionally related to a 5-nitrovanillin and an entacapone.
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(2E)-2-Cyano-3-(3-ethoxy-4-hydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide(857629-79-9)Related Product Information
- (alphaE)-alpha-[(3,4-Dihydroxy-5-nitrophenyl)methylene]-beta-oxo-1-piperidinepropanenitrile
- Entacapone EP IMpurity I
- TYRPHOSTIN AG 1290
- Entacapone EP IMpurity B
- Sodium cyanoborohydride
- Entacapone EP Impurity G
- Entacapone Impurity 10
- Entacapone Impurity 4
- 6-Methoxy-2,4-dinitrophenol
- Entacapone 3-b-D-Glucuronide
- Entacapone Impurity 13
- 2-Propenamide, 2-cyano-3-(3,4-dihydroxyphenyl)-N,N-diethyl-, (2E)-
- (E/Z)-3-O-Methyl Entacapone
- 3-Nitro-4,5-dihydroxybenzaldehyde
- CIS-ENTACAPONE
- (E)-3-O-Methyl Entacapone
- Entacapone
- 3,5-DINITROCATECHOL