MPEG11-CH2CH2COONHS
MPEG11-CH2CH2COONHS Basic information
- Product Name:
- MPEG11-CH2CH2COONHS
- Synonyms:
-
- MPEG11-CH2CH2COONHS
- 4,7,10,13,16,19,22,25,28,31,34,37-Dodecaoxaoctatriacontanoic acid, 2,5-dioxo-1-pyrrolidinyl ester
- mPEG11-CH2CH2COONHS/4,7,10,13,16,19,22,25,28,31,34,37-Dodecaoxaoctatriacontanoic acid, 2,5-dioxo-1-pyrrolidinyl ester
- CAS:
- 2207596-93-6
- MF:
- C30H55NO16
- MW:
- 685.75
- Mol File:
- 2207596-93-6.mol
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MPEG11-CH2CH2COONHS Chemical Properties
- Boiling point:
- 684.3±65.0 °C(Predicted)
- Density
- 1.19±0.1 g/cm3(Predicted)
- InChIKey
- ZMXRHHJWXLKMTL-UHFFFAOYSA-N
- SMILES
- C(ON1C(=O)CCC1=O)(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC
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MPEG11-CH2CH2COONHS Usage And Synthesis
Biological Activity
m-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
MPEG11-CH2CH2COONHSSupplier
Biomatrik (Jiaxing) Inc.
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- 573-573-82623377 18967387295
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Chengdu Pukang Biotechnology Co., Ltd
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- 028-82550498 19102685862
- sales@pu-kang.com
Beijing Jin Ming Biotechnology Co., Ltd.
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- 010-60605840 18892239720
- psaitong@jm-bio.com
Amatek Scientific Co. Ltd.
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- 0512-56316828
- info@amateksci.com
Aikon International Limited
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- 025-58859352 18068836627
- sales01@aikonchem.com