2-Azabicyclo[3.1.0]hexane-2-carboxylic acid, 3-(aMinocarbonyl)-, 1,1-diMethylethyl ester, (1S,3R,5S)- Chemical Properties

Boiling point:

388.9±21.0 °C(Predicted)

Density 

1.228±0.06 g/cm3(Predicted)

pka

16.00±0.20(Predicted)

2-Azabicyclo[3.1.0]hexane-2-carboxylic acid, 3-(aMinocarbonyl)-, 1,1-diMethylethyl ester, (1S,3R,5S)- Usage And Synthesis

Uses

tert-Butyl (1S,3R,5S)-3-Carbamoyl-2-azabicyclo[3.1.0]hexane-2-carboxylate is an intermediate in the synthesis of (2’S,2R,trans)-Saxagliptin (S143470), which is an impurity of Saxagliptin (S143500). Saxagliptin is a potent and selective reversible inhibitor of dipeptidyl peptidase-4 (DPP-IV) developed for the treatment of type 2 diabetes.

2-Azabicyclo[3.1.0]hexane-2-carboxylic acid, 3-(aMinocarbonyl)-, 1,1-diMethylethyl ester, (1S,3R,5S)-(1564266-79-0)Related Product Information

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