Basic information Safety Supplier Related

N-tert-butyl-6-chloro-4-(o-tolyl)nicotinamide

Basic information Safety Supplier Related

N-tert-butyl-6-chloro-4-(o-tolyl)nicotinamide Basic information

Product Name:
N-tert-butyl-6-chloro-4-(o-tolyl)nicotinamide
Synonyms:
  • 3-Pyridinecarboxamide, 6-chloro-N-(1,1-dimethylethyl)-4-(2-methylphenyl)-
  • NETUPITANT IST-2
  • N-?(tert-?Butyl)?-?6-?chloro-?4-?(2-?methylphenyl)?nicotinamide
  • Apremilast Impurity 125
CAS:
342417-04-3
MF:
C17H19ClN2O
MW:
302.8
Mol File:
342417-04-3.mol
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N-tert-butyl-6-chloro-4-(o-tolyl)nicotinamide Chemical Properties

storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
Appearance
White to off-white Solid
InChI
InChI=1S/C17H19ClN2O/c1-11-7-5-6-8-12(11)13-9-15(18)19-10-14(13)16(21)20-17(2,3)4/h5-10H,1-4H3,(H,20,21)
InChIKey
OMUYXAYJDVKDPJ-UHFFFAOYSA-N
SMILES
C1=NC(Cl)=CC(C2=CC=CC=C2C)=C1C(NC(C)(C)C)=O
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N-tert-butyl-6-chloro-4-(o-tolyl)nicotinamide Usage And Synthesis

Uses

N-?(tert-?Butyl)?-?6-?chloro-?4-?(2-?methylphenyl)?nicotinamide is a reagent used in the synthesis of NK1/NK3 receptor antagonists used in the treatment of depression.

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