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135270-10-9

Basic information Safety Supplier Related

135270-10-9 Basic information

Product Name:
135270-10-9
Synonyms:
  • Efinaconazole Impurity 5
  • (2S,3S)-2-(2,4-difluorophenyl)-3-methyl-2-(1H-1,2,4-triazol-1-yl)methyloxirane
  • 1-(((2S,3S)-2-(2,4-difluorophenyl)-3-methyloxiran-2-yl)methyl)-1H-1,2,4-triazole
  • Efinaconazole Related Impurity 5
  • Efinaconazole Impurity 20
  • 1H-1,2,4-Triazole, 1-[[(2S,3S)-2-(2,4-difluorophenyl)-3-methyloxiranyl]methyl]- (9CI)
  • 1-[[(2S,3S)-2-(2,4-difluorophenyl)-3-methyloxiranyl]methyl]-1H-1,2,4-Triazole
  • 1-(((2S,3S)-2-(2,4-Difluorophenyl)-3-methyloxiran-2-yl)methyl)-1H-1,2,4-triazole (Efinaconazole Impurity)
CAS:
135270-10-9
MF:
C12H11F2N3O
MW:
251.23
Mol File:
135270-10-9.mol
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135270-10-9 Chemical Properties

Boiling point:
371.6±52.0 °C(Predicted)
Density 
1.41±0.1 g/cm3(Predicted)
pka
2.75±0.10(Predicted)
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135270-10-9 Usage And Synthesis

Uses

(2S,3S)-2-(2,4-Difluorophenyl)-3-methyl-2-[(1H-1,2,4-triazol-1-yl)methyl]oxirane is a useful synthetic intermediate in the synthesis of (2S,3R)-Efinaconazole (E435085); the 2S,3R-enantiomer of Efinaconazole (E435070) which is a topical antifungal for onychomycosis.

135270-10-9Supplier

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