Poricoic acid A(F)
Poricoic acid A(F) Basic information
- Product Name:
- Poricoic acid A(F)
- Synonyms:
-
- Poricoic acid A(F)
- Poricoic acid A
- Poricoic acid B
- poricoic acid F
- (2R,3R,3aR,6S,7S,9bR)-3-[(1R)-1-Carboxy-5-methyl-4-methylenehexyl]-2,3,3a,4,6,7,8,9b-octahydro-2-hydroxy-3a,6,9b-trimethyl-7-(1-methylethenyl)-1H-benz[e]indene-6-propanoic acid
- 1H-Benz[e]indene-6-propanoic acid, 3-[(1R)-1-carboxy-5-methyl-4-methylenehexyl]-2,3,3a,4,6,7,8,9b-octahydro-2-hydroxy-3a,6,9b-trimethyl-7-(1-methylethenyl)-, (2R,3R,3aR,6S,7S,9bR)-
- (+)-poricoic acid A
- (R)-2-((2R,3R,3aR,6S,7S,9bR)-6-(2-Carboxyethyl)-2-hydroxy-3a,6,9b-trimethyl-7-(prop-1-en-2-yl)-2,3,3a,4,6,7,8,9b-octahydro-1H-cyclopenta[a]naphthalen-3-yl)-6-methyl-5-methyleneheptanoic acid
- CAS:
- 137551-38-3
- MF:
- C31H46O5
- MW:
- 498.69
- Mol File:
- 137551-38-3.mol
Poricoic acid A(F) Chemical Properties
- Boiling point:
- 664.0±55.0 °C(Predicted)
- Density
- 1.11±0.1 g/cm3(Predicted)
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- Powder
- pka
- 4.63±0.10(Predicted)
- color
- White to off-white
Poricoic acid A(F) Usage And Synthesis
Uses
Poricoic acid A, isolated from Poria cocos, possesses anti-tumor activity[1]. Poricoic acid A enhances melatonin inhibition of AKI-to-CKD transition by regulating Gas6/AxlNFκB/Nrf2 axis[2].
Definition
ChEBI: Poricoic acid A is a tricyclic triterpenoid isolated from Poria cocos. It has a role as a fungal metabolite. It is a tricyclic triterpenoid, a dicarboxylic acid and a secondary alcohol.
target
Immunology & Inflammation related
References
[1] Dong H, et al. Enrichment and separation of antitumor triterpene acids from the epidermis of Poria cocos by pH-zone-refining counter-current chromatography and conventional high-speed counter-current chromatography. J Sep Sci. 2015 Jun;38(11):1977-82. DOI:10.1002/jssc.201500077
[2] Chen DQ, et al. Poricoic acid A enhances melatonin inhibition of AKI-to-CKD transition by regulating Gas6/AxlNFκB/Nrf2 axis. Free Radic Biol Med. 2019 Apr;134:484-497. DOI:10.1016/j.freeradbiomed.2019.01.046
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Poricoic acid A(F)(137551-38-3)Related Product Information
- dehydrotumulosic acid
- PoMolic acid 28-O-beta-D-glucopyranosyl ester
- 3-O-Acetyl-16α-hydroxydehydrotrametenolic acid
- Asiaticoside B
- poricoic acid B
- bakkenolide A
- SWERTIANOLIN
- APIGENIN 6-GLUCOSYL-7-O-METHYL ETHER
- Jaceosidin
- Polygalasaponin XXXI
- GARDENOSIDE
- HUMULONE
- dichotomitin
- caesalpin J
- HARRINGTONINE
- Isoastragaloside II
- poricoic acid A 3-methyl ester
- PACHYMARAN