3,5-Diiodo-L-thyronine
3,5-Diiodo-L-thyronine Basic information
- Product Name:
- 3,5-Diiodo-L-thyronine
- Synonyms:
-
- 3,5-Diiodi-L-thyronine
- 3,5-DIIODO-L -THYRONINE 98%
- 3,5-Diiodo-4-(4-hydroxyphenoxy)-L-phenylalanine, O-(4-Hydroxyphenyl)-3,5-diiodo-L-tyrosine
- 3,5-Diiodo-O-(4-hydroxyphenyl)-L-tyrosine
- L-Diiodothyronine
- Alanine, 3-[4-(p-hydroxyphenoxy)-3,5-diiodophenyl]-, L-
- Diiodo-L-thyronine
- L-3,5-Diiodothyronine
- CAS:
- 1041-01-6
- MF:
- C15H13I2NO4
- MW:
- 525.08
- EINECS:
- 213-867-7
- Product Categories:
-
- Amino Acids 13C, 2H, 15N
- Amino Acids & Derivatives
- Medicine intermediate
- Intermediates
- Labeling and Diagnostics Reagents
- Mol File:
- 1041-01-6.mol
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3,5-Diiodo-L-thyronine Chemical Properties
- Melting point:
- 255-260 °C (dec.)
- Boiling point:
- 559.4±50.0 °C(Predicted)
- Density
- 2.095±0.06 g/cm3(Predicted)
- vapor pressure
- 0.011Pa at 45℃
- storage temp.
- Keep in dark place,Sealed in dry,Store in freezer, under -20°C
- solubility
- Acidic Alcohol (Slightly), Aqueous Base (Slightly)
- form
- Solid
- pka
- 2.15±0.30(Predicted)
- color
- White to Light Brown
- Water Solubility
- 20.147mg/L at 20℃
- BRN
- 2707891
- Stability:
- Hygroscopic
- InChIKey
- ZHSOTLOTTDYIIK-ZDUSSCGKSA-N
- LogP
- 1.1 at 25℃
- CAS DataBase Reference
- 1041-01-6(CAS DataBase Reference)
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MSDS
- Language:English Provider:SigmaAldrich
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3,5-Diiodo-L-thyronine Usage And Synthesis
Chemical Properties
[α] 25 D +25.2° [5 % solution in 1 M HCl:95 % ethanol (1:2)], off-White Solid.
Uses
3,5-Diiodo-L-thyronine is an iodinated thyronine hormone that regulates gene activity affecting processes such as homeostasis, lipid metabolism and insulin resistance.
Uses
Of interest for the early detection and treatment of congenital or drug-induced hypothyroidism.
Definition
ChEBI: (2S)-2-amino-3-[4-(4-hydroxyphenoxy)-3,5-diiodophenyl]propanoic acid is a phenylalanine derivative.
Flammability and Explosibility
Not classified
Pharmacology
3,5-Diiodo-L-thyronine is a thyroid hormone with a l-thyroxine-like activity.
Purification Methods
Recrystallise it from EtOH. [Chambers et al. J Chem Soc 3424 1949, Beilstein 14 II 226, 14 III 1565, 14 IV 2372.]
3,5-Diiodo-L-thyronineSupplier
Suzhou Ryan Pharmaceutical Technology Co., Ltd. Gold
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3B Pharmachem (Wuhan) International Co.,Ltd.
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- 821-50328103-801 18930552037
- 3bsc@sina.com
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3,5-Diiodo-L-thyronine(1041-01-6)Related Product Information
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- L-Thyroxine
- L(+)-Arginine
- TSH
- REVERSE T3
- 3,3',5-Triiodo-L-thyronine
- Inositol
- DL-THYROXINE
- Levothyroxine Impurity 12
- 3,3',5-TRIIODOTHYROPROPIONIC ACID
- Thyroxine-4-hydroxy-3,5-diiodophenyl Ether DISCONTINUED
- 3,5-DIIODO-4'-(4-HYDROXYPHENOXY)BENZOIC ACID
- N-ForMyl Thyroxine
- 3,5,3',5'-Tetraiodo Thyroaldehyde
- 3-IODO-L-TYROSINE
- 3,3',5,5'-TETRAIODOTHYRO-ACETIC ACID